Miscellaneous meroterpenoids from Ganoderma applanatum

doi:10.1016/j.tet.2016.06.019

	Miscellaneous meroterpenoids from Ganoderma applanatum
	Luo, Qi; Yang, Xiao-Hua; Yang, Zhu-Liang; Tu, Zheng-Chao; Cheng, Yong-Xian
	2016-07-28
发表期刊	TETRAHEDRON
卷号	72 期号:30 页码:4564-4574
摘要	Twenty-six new meroterpenoids, applanatumols C-Z (1-24), Zl (25) and Z2 (26), and three new alkaloids, ganoapplanatumines A (27), B (28) and epi-ganoapplanatumine B (29), were isolated from the fruiting bodies of Ganoderma applanatum. With exception of 18 and 25, all the other compounds are racemates, Chiral HPLC separation afforded their respective enantiomers. The structures of these isolates including their absolute configurations were assigned by spectroscopic and computational methods. In particular, the structures of 1, 3 and 12 were confirmed by single crystal X-ray diffraction data. Biological activities of all the isolates against COX-1 and COX-2 were evaluated, compound la was found to have COX-2 inhibitory effect with IC50 value of 25.5 mu M. (C) 2016 Elsevier Ltd. All rights reserved.
关键词	Ganoderma Applanatum Meroterpenoids Alkaloids Cox-1/2
DOI	10.1016/j.tet.2016.06.019
收录类别	SCI
语种	英语
WOS记录号	WOS:000380073300012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/28490
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Luo, Qi,Yang, Xiao-Hua,Yang, Zhu-Liang,et al. Miscellaneous meroterpenoids from Ganoderma applanatum[J]. TETRAHEDRON,2016,72(30):4564-4574.
APA	Luo, Qi,Yang, Xiao-Hua,Yang, Zhu-Liang,Tu, Zheng-Chao,&Cheng, Yong-Xian.(2016).Miscellaneous meroterpenoids from Ganoderma applanatum.TETRAHEDRON,72(30),4564-4574.
MLA	Luo, Qi,et al."Miscellaneous meroterpenoids from Ganoderma applanatum".TETRAHEDRON 72.30(2016):4564-4574.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
1-s2.0-S004040201630（1597KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载