Three New Pregnane Alkaloids from Pachysandra terminalis

doi:10.1002/hlca.201600016

	Three New Pregnane Alkaloids from Pachysandra terminalis
	Sun, Yun; Chen, Jin-Xiong; Chen, Jian-Chao; Li, Zhong-Rong; Zhou, Lin; Li, Yan; Qiu, Ming-Hua
	2016-07-01
发表期刊	HELVETICA CHIMICA ACTA
卷号	99 期号:7 页码:513-517
摘要	Three new pregnane alkaloids, pachystermine C (1), pachysanamine A (2), and pachysanamine B (3), together with four known ones, pachystermine B (4), pachysamine A (5), (20S)-20-(dimethylamino)-16-hydroxy-3-(3-isopropyl)lactam-5-pregnan-4-one (6), and E-salignone (7), were isolated from Pachysandra terminalis. The chemical structures of the new alkaloids were elucidated by spectroscopic methods. All the compounds were evaluated for their inhibitory activities against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, some of the compounds showed stronger cytotoxicity for the test cell lines, especially compounds 2, 3, and 7.
关键词	Pregnane Alkaloids Buxaceae Pachysandra Terminalis Cytotoxicity
DOI	10.1002/hlca.201600016
收录类别	SCI
语种	英语
WOS记录号	WOS:000379937300005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/28488
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Sun, Yun,Chen, Jin-Xiong,Chen, Jian-Chao,et al. Three New Pregnane Alkaloids from Pachysandra terminalis[J]. HELVETICA CHIMICA ACTA,2016,99(7):513-517.
APA	Sun, Yun.,Chen, Jin-Xiong.,Chen, Jian-Chao.,Li, Zhong-Rong.,Zhou, Lin.,...&Qiu, Ming-Hua.(2016).Three New Pregnane Alkaloids from Pachysandra terminalis.HELVETICA CHIMICA ACTA,99(7),513-517.
MLA	Sun, Yun,et al."Three New Pregnane Alkaloids from Pachysandra terminalis".HELVETICA CHIMICA ACTA 99.7(2016):513-517.

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