Three New Pregnane Alkaloids from Pachysandra terminalis
Sun, Yun; Chen, Jin-Xiong; Chen, Jian-Chao; Li, Zhong-Rong; Zhou, Lin; Li, Yan; Qiu, Ming-Hua
2016-07-01
发表期刊HELVETICA CHIMICA ACTA
卷号99期号:7页码:513-517
摘要Three new pregnane alkaloids, pachystermine C (1), pachysanamine A (2), and pachysanamine B (3), together with four known ones, pachystermine B (4), pachysamine A (5), (20S)-20-(dimethylamino)-16-hydroxy-3-(3-isopropyl)lactam-5-pregnan-4-one (6), and E-salignone (7), were isolated from Pachysandra terminalis. The chemical structures of the new alkaloids were elucidated by spectroscopic methods. All the compounds were evaluated for their inhibitory activities against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, some of the compounds showed stronger cytotoxicity for the test cell lines, especially compounds 2, 3, and 7.
关键词Pregnane Alkaloids Buxaceae Pachysandra Terminalis Cytotoxicity
DOI10.1002/hlca.201600016
收录类别SCI
语种英语
WOS记录号WOS:000379937300005
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/28488
专题植物化学与西部植物资源持续利用国家重点实验室
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Sun, Yun,Chen, Jin-Xiong,Chen, Jian-Chao,et al. Three New Pregnane Alkaloids from Pachysandra terminalis[J]. HELVETICA CHIMICA ACTA,2016,99(7):513-517.
APA Sun, Yun.,Chen, Jin-Xiong.,Chen, Jian-Chao.,Li, Zhong-Rong.,Zhou, Lin.,...&Qiu, Ming-Hua.(2016).Three New Pregnane Alkaloids from Pachysandra terminalis.HELVETICA CHIMICA ACTA,99(7),513-517.
MLA Sun, Yun,et al."Three New Pregnane Alkaloids from Pachysandra terminalis".HELVETICA CHIMICA ACTA 99.7(2016):513-517.
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