| (+)- and (-)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum | |
Chen, He-Ping1,3; Zhao, Zhen-Zhu1,3; Zhang, Yu1 ; Bai, Xue1; Zhang, Ling1; Liu, Ji-Kai1,2
| |
| 2016 | |
| 发表期刊 | RSC ADVANCES
 |
| 卷号 | 6期号:69页码:64469-64473 |
| 摘要 | (+)- and (-)-Ganodilactone (1), a pair of novel meroterpenoid dimers possessing a unique 5'H-spiro [chroman-4,2'-furan]-2,5'-dione ring system, along with their biogeneticly-related compound, ganomycin I (2), were discovered from the fruiting bodies of Ganoderma leucocontextum. The structures and absolute configurations were assigned with the aid of 1D and 2D NMR spectra, HRESIMS analysis and ECD calculations. (+/-)-, (+)-, and (-)-ganodilactone (1) showed pancreatic lipase inhibitory activities and exhibited the IC50 values as 27.3, 4.0, and 2.5 mu M, respectively. |
| DOI | 10.1039/c6ra10638b |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000379442400038 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/28463 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, He-Ping,Zhao, Zhen-Zhu,Zhang, Yu,et al. (+)- and (-)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum[J]. RSC ADVANCES,2016,6(69):64469-64473. |
| APA | Chen, He-Ping,Zhao, Zhen-Zhu,Zhang, Yu,Bai, Xue,Zhang, Ling,&Liu, Ji-Kai.(2016).(+)- and (-)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum.RSC ADVANCES,6(69),64469-64473. |
| MLA | Chen, He-Ping,et al."(+)- and (-)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum".RSC ADVANCES 6.69(2016):64469-64473. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 10.1039@c6ra10638b.p（768KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
| 10.1039@c6ra10638b.p（768KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论