Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336
Yu, Fei-Xue1,2,3; Chen, Yao3; Yang, Yin-He4; Zhao, Pei-Ji1,2,4
2016-06-01
Source PublicationPHYTOCHEMISTRY LETTERS
Volume16Pages:263-267
AbstractChaetomium sp. M336 was isolated from Huperzia serrata (Thunb. ex Murray) Trev. and subjected to phytochemical investigation based on its special environment. To understand the secondary metabolites of strain Chaetomium sp. M336, four new dimeric spiro-azaplilone derivatives cochliodones E-H (1-4) were isolated from solid fermentation products of the fungus, which were elucidated by extensive spectroscopic analyses, including 1D- and 2D NMR, and HR-ESI-MS experiments. The antibacterial activities of compounds 1-4 against bacteria were tested in vitro. They exhibited antibacterial activities against Escherichia coli, Staphylococcus aureus, Salmonella typhimurium ATCC 6539 and Enterococcus faecalis with minimum inhibitory concentration (MIC) values of 0.78-100 mu g/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
KeywordChaetomium Sp M336 Chemical Constituents Structure Identification Cochliodone Antibacterial Activities
DOI10.1016/j.phytol.2016.05.003
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS IDWOS:000378027300047
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/26286
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ, Minist Educ, Lab Conservat & Utilizat Bioresource, Kunming 650091, Peoples R China
2.Yunnan Univ, Minist Educ, Key Lab Microbial Resources, Kunming 650091, Peoples R China
3.Kunming Univ Sci & Technol, Fac Med, Kunming 650500, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
Recommended Citation
GB/T 7714
Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,et al. Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336[J]. PHYTOCHEMISTRY LETTERS,2016,16:263-267.
APA Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,&Zhao, Pei-Ji.(2016).Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336.PHYTOCHEMISTRY LETTERS,16,263-267.
MLA Yu, Fei-Xue,et al."Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336".PHYTOCHEMISTRY LETTERS 16(2016):263-267.
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