| LC-MS guided isolation of ent-kaurane diterpenoids from Nouelia insignis | |
Sun, Chang-Li1,2; Geng, Chang-An1 ; Chen, Xing-Long1,2; Yang, Tong-Hua1,2; Yin, Xiu-Juan1,2; Huang, Xiao-Yan1; Peng, Hua3; Chen, Ji-Jun1
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| 2016-06-01 | |
| 发表期刊 | FITOTERAPIA
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| 卷号 | 111页码:42-48 |
| 摘要 | The preliminary LC-MS investigation on the stems of Nouelia insignis manifested the existence of diterpenoids. As a result, 15 ent-kaurane diterpenoids, including 7 new glycosides (nouelosides A-G, 1-7), were isolated under the direction of LC-MS analysis. The new compounds were determined by extensive spectroscopic analysis including HRESIMS, 1D and 2D NMR data and chemical methods. Compounds 6 and 15 with the exo-methylene cyclopentanone functional group exhibited obvious nitric oxide production inhibitory activity with IC50 values of 3.84 +/- 0.20 and 3.19 +/- 0.25 mu M. (C) 2016 Elsevier B.V. All rights reserved. |
| 关键词 | Nouelia Insignis Lc-ms Diterpenoids Nitric Oxide Production Inhibitory Activity |
| DOI | 10.1016/j.fitote.2016.04.003 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000377834300008 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/26279 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Key Lab Biodivers & Biogeog, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Chang-Li,Geng, Chang-An,Chen, Xing-Long,et al. LC-MS guided isolation of ent-kaurane diterpenoids from Nouelia insignis[J]. FITOTERAPIA,2016,111:42-48. |
| APA | Sun, Chang-Li.,Geng, Chang-An.,Chen, Xing-Long.,Yang, Tong-Hua.,Yin, Xiu-Juan.,...&Chen, Ji-Jun.(2016).LC-MS guided isolation of ent-kaurane diterpenoids from Nouelia insignis.FITOTERAPIA,111,42-48. |
| MLA | Sun, Chang-Li,et al."LC-MS guided isolation of ent-kaurane diterpenoids from Nouelia insignis".FITOTERAPIA 111(2016):42-48. |
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