Antiplasmodial Activity and Cytotoxicity of Isolated Compound from the Stem Bark of Anthocleista liebrechtsiana
Kowa, Theodora K.1,2; Zofou, Denis3; Mbouangouere, Roukayatou1; Tala, Michel F.1,4; Wabo, Hippolyte K.1; Tan, Ning-Hua4; Titanji, Vincent P. K.3; Tane, Pierre1
2016
Source PublicationRECORDS OF NATURAL PRODUCTS
Volume10Issue:3Pages:287-293
AbstractOne new cerebroside derivative, namely liebrechtsianoside A (1), along with five known compounds: tetracosanoic acid (2), swertiaperennin (3), decussatin (4), swertianin (5) and beta-sitosterol glucoside (6) were isolated from the the stem bark of Anthocleista liebrechtsiana. Their structures were elucidated by interpretation of NMR and MS data, and by comparison of these data with those reported in literature. Compound 1 showed the highest antiplasmodial activity against Dd2 chloroquine-resistant strain of Plasmodium falciparum.
KeywordAnthocleista Liebrechtsiana Loganiaceae Cerebroside Structure Elucidation Antiplasmodial Activity
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Applied ; Chemistry, Medicinal
WOS IDWOS:000372803000003
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/26274
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Univ Dschang, Fac Sci, Dept Chem, POB 67, Dschang, Cameroon
2.Inst Med Res & Med Plants Studies IMPM, POB 6163, Yaounde, Cameroon
3.Univ Buea, Biotechnol Unit, POB 63, Buea, Cameroon
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Kowa, Theodora K.,Zofou, Denis,Mbouangouere, Roukayatou,et al. Antiplasmodial Activity and Cytotoxicity of Isolated Compound from the Stem Bark of Anthocleista liebrechtsiana[J]. RECORDS OF NATURAL PRODUCTS,2016,10(3):287-293.
APA Kowa, Theodora K..,Zofou, Denis.,Mbouangouere, Roukayatou.,Tala, Michel F..,Wabo, Hippolyte K..,...&Tane, Pierre.(2016).Antiplasmodial Activity and Cytotoxicity of Isolated Compound from the Stem Bark of Anthocleista liebrechtsiana.RECORDS OF NATURAL PRODUCTS,10(3),287-293.
MLA Kowa, Theodora K.,et al."Antiplasmodial Activity and Cytotoxicity of Isolated Compound from the Stem Bark of Anthocleista liebrechtsiana".RECORDS OF NATURAL PRODUCTS 10.3(2016):287-293.
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