| Schoberine B, an alkaloid with an unprecedented straight C-5 side chain, and myriberine B from Myrioneuron faberi | |
Cao, Ming-Ming1,2; Zhang, Yu1 ; Peng, Zong-Gen3,4; Jiang, Jian-Dong3,4; Gao, Yue-Jiao2; Hao, Xiao-Jiang1
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| 2016 | |
| 发表期刊 | RSC ADVANCES
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| 卷号 | 6期号:12页码:10180-10184 |
| 摘要 | Two novel Myrioneuron alkaloids, schoberine B (1) and myriberine B (2), were isolated from the aerial part of Myrioneuron faberi. Schoberine B is the first example among lysine-originating alkaloids to possess a ring-free C-5 fragment as a side chain. The structures of 1 and 2 were elucidated using analyses of extensive NMR and MS spectra. 1 and 2 were evaluated in vitro against hepatitis C virus (HCV), showing a therapeutic index (CC50/EC50) of higher than 36.2 and 15.2, respectively. |
| DOI | 10.1039/c5ra25218k |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000369516100097 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/25961 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China 3.Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Ming-Ming,Zhang, Yu,Peng, Zong-Gen,et al. Schoberine B, an alkaloid with an unprecedented straight C-5 side chain, and myriberine B from Myrioneuron faberi[J]. RSC ADVANCES,2016,6(12):10180-10184. |
| APA | Cao, Ming-Ming,Zhang, Yu,Peng, Zong-Gen,Jiang, Jian-Dong,Gao, Yue-Jiao,&Hao, Xiao-Jiang.(2016).Schoberine B, an alkaloid with an unprecedented straight C-5 side chain, and myriberine B from Myrioneuron faberi.RSC ADVANCES,6(12),10180-10184. |
| MLA | Cao, Ming-Ming,et al."Schoberine B, an alkaloid with an unprecedented straight C-5 side chain, and myriberine B from Myrioneuron faberi".RSC ADVANCES 6.12(2016):10180-10184. |
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