1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum

doi:10.1021/acs.jnatprod.5b00830

	1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum
	Zhang, Jing-Jing; Yang, Xing-Wei; Liu, Xia; Ma, Jun-Zeng; Liao, Yang; Xu, Gang
	2015-12-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
卷号	78 期号:12 页码:3075-3079
摘要	Hyperuralones C-H (1-6), six new 1,9-seco-bicyclic polyprenylated acylphloroglucinols (1,9-seco-BPAPs) derived from the normal polyprenylated acylphloroglucinols with a bicyclo[3.3.1]nonane-2,4,9-trione core, together with six known analogues, were isolated from the aerial parts of Hypericum uralum. The structures of 1-6 were elucidated on the basis of the interpretation of NMR. and MS spectroscopic data. The structure of attenuatumione B, a known compound isolated from H. attenuatum, was revised to that of a 1,9-seco-BPAP by NMR spectroscopic analysis and previous biomimetic synthesis methods. The inhibitory activities of these isolates on acetylcholinesterase were tested, and compounds 1 and 2 exhibited moderate activities with IC50 values of 9.6 and 7.1 mu M, respectively.
DOI	10.1021/acs.jnatprod.5b00830
收录类别	SCI
语种	英语
WOS记录号	WOS:000367562600027
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25442
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Zhang, Jing-Jing,Yang, Xing-Wei,Liu, Xia,et al. 1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(12):3075-3079.
APA	Zhang, Jing-Jing,Yang, Xing-Wei,Liu, Xia,Ma, Jun-Zeng,Liao, Yang,&Xu, Gang.(2015).1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum.JOURNAL OF NATURAL PRODUCTS,78(12),3075-3079.
MLA	Zhang, Jing-Jing,et al."1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum".JOURNAL OF NATURAL PRODUCTS 78.12(2015):3075-3079.

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