1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum | |
Zhang, Jing-Jing; Yang, Xing-Wei; Liu, Xia; Ma, Jun-Zeng; Liao, Yang; Xu, Gang | |
2015-12-01 | |
发表期刊 | JOURNAL OF NATURAL PRODUCTS |
卷号 | 78期号:12页码:3075-3079 |
摘要 | Hyperuralones C-H (1-6), six new 1,9-seco-bicyclic polyprenylated acylphloroglucinols (1,9-seco-BPAPs) derived from the normal polyprenylated acylphloroglucinols with a bicyclo[3.3.1]nonane-2,4,9-trione core, together with six known analogues, were isolated from the aerial parts of Hypericum uralum. The structures of 1-6 were elucidated on the basis of the interpretation of NMR. and MS spectroscopic data. The structure of attenuatumione B, a known compound isolated from H. attenuatum, was revised to that of a 1,9-seco-BPAP by NMR spectroscopic analysis and previous biomimetic synthesis methods. The inhibitory activities of these isolates on acetylcholinesterase were tested, and compounds 1 and 2 exhibited moderate activities with IC50 values of 9.6 and 7.1 mu M, respectively. |
DOI | 10.1021/acs.jnatprod.5b00830 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000367562600027 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/25442 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Zhang, Jing-Jing,Yang, Xing-Wei,Liu, Xia,et al. 1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(12):3075-3079. |
APA | Zhang, Jing-Jing,Yang, Xing-Wei,Liu, Xia,Ma, Jun-Zeng,Liao, Yang,&Xu, Gang.(2015).1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum.JOURNAL OF NATURAL PRODUCTS,78(12),3075-3079. |
MLA | Zhang, Jing-Jing,et al."1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum".JOURNAL OF NATURAL PRODUCTS 78.12(2015):3075-3079. |
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