Alkaloids with Different Carbon Units from Myrioneuron faberi

doi:10.1021/acsj.natprod.5b00543

	Alkaloids with Different Carbon Units from Myrioneuron faberi
	Cao,Ming-Ming; Zhang,Yu; Huang,Sheng-Dian; Di,Ying-Tong; Peng,Zong-Gen; Jiang,Jian-Dong; Yuan,Chun-Mao; Chen,Duo-Zhi; Li,Shun-Lin; He,Hong-Ping; Hao,Xiao-Jiang
	2015-11-01
发表期刊	JOURNAL OF NATURAL PRODUCTS
卷号	78 期号:11 页码:2609-2616
摘要	Three new Myrioneuron alkaloids, myrifamines A-C (1-3), with unique skeletons were isolated from Myrioneuron faberi. The absolute configuration of 1 was confirmed by single-crystal X-ray diffraction analysis, and the stereochemistry of the other two alkaloids was determined using a combination of ROESY experiments and calculated and experimental electronic circular dichroism spectra. Myrifamine C (3) is the first example of a symmetric dimer among the Myrioneuron alkaloids. Known alkaloids myrionamide (4) and schoberine (5) were also isolated, and experimental NMR and X-ray diffraction data suggest their structural revision. Compound 2 showed significant inhibitory activity toward the hepatitis C virus in vitro, with a therapeutic index (CC50/EC50) greater than 108.7.
DOI	10.1021/acsj.natprod.5b00543
收录类别	SCI
语种	英语
WOS记录号	WOS:000366005800013
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25266
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Cao,Ming-Ming,Zhang,Yu,Huang,Sheng-Dian,et al. Alkaloids with Different Carbon Units from Myrioneuron faberi[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(11):2609-2616.
APA	Cao,Ming-Ming.,Zhang,Yu.,Huang,Sheng-Dian.,Di,Ying-Tong.,Peng,Zong-Gen.,...&Hao,Xiao-Jiang.(2015).Alkaloids with Different Carbon Units from Myrioneuron faberi.JOURNAL OF NATURAL PRODUCTS,78(11),2609-2616.
MLA	Cao,Ming-Ming,et al."Alkaloids with Different Carbon Units from Myrioneuron faberi".JOURNAL OF NATURAL PRODUCTS 78.11(2015):2609-2616.

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