Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells
Dong,Fa-Wu; Wu,Zhi-Kun; Yang,Liu; Zi,Chen-Ting; Yang,Dan; Ma,Rui-Jing; Liu,Zhen-Hua; Luo,Huai-Rong; Zhou,Jun; Hu,Jiang-Miao
2015-10-01
发表期刊PHYTOCHEMISTRY
卷号118页码:51-60
摘要Twenty-one compounds (nine iridoids and twelve sesquiterpenoids), including ten previously unknown (five iridoids and five sesquiterpenoids) were isolated from whole dried material of Valeriana stenoptera. Structures were established on the basis of extensive spectroscopic analysis and the relative stereochemistry of 13-hydroxypatchoulol A was further confirmed by X-ray crystallographic data. All isolates were evaluated for their effects on nerve growth factor (NGF)-mediated neurite outgrowth in pheochromocytoma (PC12) cells and seven compounds showed potent promoting effects. (C) 2015 Elsevier Ltd. All rights reserved.
关键词Valeriana Stenoptera Valerianaceae Iridoids Sesquiterpenoids Biological Activity
DOI10.1016/j.phytochem.2015.08.015
收录类别SCI
语种英语
WOS记录号WOS:000363076800007
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/25201
专题植物化学与西部植物资源持续利用国家重点实验室
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Dong,Fa-Wu,Wu,Zhi-Kun,Yang,Liu,et al. Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells[J]. PHYTOCHEMISTRY,2015,118:51-60.
APA Dong,Fa-Wu.,Wu,Zhi-Kun.,Yang,Liu.,Zi,Chen-Ting.,Yang,Dan.,...&Hu,Jiang-Miao.(2015).Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells.PHYTOCHEMISTRY,118,51-60.
MLA Dong,Fa-Wu,et al."Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells".PHYTOCHEMISTRY 118(2015):51-60.
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