Chemical constituents from Euphorbia wallichii and their biological activities

doi:10.1080/10286020.2015.1038525

	Chemical constituents from Euphorbia wallichii and their biological activities
	Yang,Da-Song; Peng,Wei-Bing; Yang,Yong-Ping; Liu,Ke-Chun; Li,Xiao-Li; Xiao,Wei-Lie
	2015-09-02
发表期刊	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷号	17 期号:9 页码:946-951
摘要	One rare diterpenoid which was an unusual phorbol derivative possessing a 5-ene-7-oxo functional group, wallichiioid A (1), and 17 known compounds (2-18) were isolated from the aerial parts of Euphorbia wallichii. The structures and relative configuration of these compounds were elucidated on the basis of extensive spectroscopic interpretation. All the known compounds were isolated from E. wallichii for the first time. Diterpenoids 1-5 were tested for their cytotoxicity against five cancer cell lines (A-549, MCF-7, Hep G2, HeLa, and P388) and showed IC50 values in the range of 8.19-29.72g/mL. The antiangiogenic activities of diterpenoids 1-5 were also evaluated using a zebrafish model.
关键词	Euphorbia Wallichii Diterpenoid Wallichiioid a Cytotoxicity Antiangiogenic Activities
DOI	10.1080/10286020.2015.1038525
收录类别	SCI
语种	英语
WOS记录号	WOS:000361969800010
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/25165
专题	资源植物与生物技术所级重点实验室
推荐引用方式 GB/T 7714	Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,et al. Chemical constituents from Euphorbia wallichii and their biological activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2015,17(9):946-951.
APA	Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,Liu,Ke-Chun,Li,Xiao-Li,&Xiao,Wei-Lie.(2015).Chemical constituents from Euphorbia wallichii and their biological activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,17(9),946-951.
MLA	Yang,Da-Song,et al."Chemical constituents from Euphorbia wallichii and their biological activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 17.9(2015):946-951.

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