| Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD | |
Ge, Guang-Bo1,2; Liang, Si-Cheng1; Hu, Ying1; Liu, Xing-Bao1; Mao, Yu-Xi1,2; Zhang, Yan-Yan1,2; Luan, Hong-Wei1; Qiu, Ming-Hua3 ; Yang, Ling1
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| 2010-10-01 | |
| 发表期刊 | PLANTA MEDICA
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| 卷号 | 76期号:15页码:1773-1777 |
| 摘要 | The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots from various Taxus species. All target analytes could be identified by comparing their retention times as well as UV and MS spectra with authentic standards, while seven valuable taxanes in botanical samples can be rapidly determined by UFLC-DAD with excellent sensitivity. Analysis of more than one hundred yew samples from nine species showed significant variations in distribution and content of seven evaluated taxanes. Thus, different developmental schemes should be used for better utilization of various yew resources. |
| 关键词 | Taxaceae Taxus Yew Taxane Paclitaxel Target Analysis |
| DOI | 10.1055/s-0030-1249959 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000283917300028 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/23906 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ge, Guang-Bo,Liang, Si-Cheng,Hu, Ying,et al. Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD[J]. PLANTA MEDICA,2010,76(15):1773-1777. |
| APA | Ge, Guang-Bo.,Liang, Si-Cheng.,Hu, Ying.,Liu, Xing-Bao.,Mao, Yu-Xi.,...&Yang, Ling.(2010).Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD.PLANTA MEDICA,76(15),1773-1777. |
| MLA | Ge, Guang-Bo,et al."Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD".PLANTA MEDICA 76.15(2010):1773-1777. |
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| s-0030-1249959.pdf（121KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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