Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica
Li, Ting1; Hao, Xiao-Jiang2; Gu, Qian-Qun1; Zhu, Wei-Ming1
2008-09-01
发表期刊PLANTA MEDICA
卷号74期号:11页码:1391-1396
摘要Four new furofurano lignans, lantibesides B-D (1-3) and lantibetin (4), along with nine known phenolic compounds were isolated from the EtOH extract of the traditional Tibetan medicinal plant, Lancea tibetica. By means of spectroscopic and chemical methods, the structures of the new compounds were elucidated as (1R,2S,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-[(3-methoxy-4- beta-D-xylopyranosyloxy(1 -> 6)-beta-D-glucopyranosyloxy)phenyl ]-3,7-dioxabicyclo[3.3.0]octane (1), (1R,2R,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-[(3-methoxy-4-beta-D-xylopyranosyloxy(1 -> 6)-beta-D-glucopyranosyloxy)phenyl]-3,7-dioxabicyclo [3.3.0]octane (2), (1R,2R,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-beta-D-glucopyra-nosyloxy)phenyl-3,7-dioxabicyclo[3.3.0] octane (3), and (1R,2R,5R,6S)-2-(3,4-dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-dioxabicyclo[3.3.0] octane (4). Compounds 2 and 3 showed weak cytotoxicity against the HL-60 cell line with IC50 values of 61 and 99 mu M, respectively.
关键词Lancea Tibetica Phrymaceae Cytotoxicity Furofurano Lignin Lantibeside Lantibetin
DOI10.1055/s-2008-1081308
收录类别SCI
语种英语
WOS记录号WOS:000260174300012
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/23876
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Ocean Univ China, Chinese Minist Educ, Sch Med & Pharm, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming, Peoples R China
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Li, Ting,Hao, Xiao-Jiang,Gu, Qian-Qun,et al. Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica[J]. PLANTA MEDICA,2008,74(11):1391-1396.
APA Li, Ting,Hao, Xiao-Jiang,Gu, Qian-Qun,&Zhu, Wei-Ming.(2008).Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica.PLANTA MEDICA,74(11),1391-1396.
MLA Li, Ting,et al."Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica".PLANTA MEDICA 74.11(2008):1391-1396.
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