Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica

doi:10.1055/s-2008-1081308

	Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica
	Li, Ting 1; Hao, Xiao-Jiang2 ; Gu, Qian-Qun 1; Zhu, Wei-Ming 1
	2008-09-01
发表期刊	PLANTA MEDICA
卷号	74 期号:11 页码:1391-1396
摘要	Four new furofurano lignans, lantibesides B-D (1-3) and lantibetin (4), along with nine known phenolic compounds were isolated from the EtOH extract of the traditional Tibetan medicinal plant, Lancea tibetica. By means of spectroscopic and chemical methods, the structures of the new compounds were elucidated as (1R,2S,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-[(3-methoxy-4- beta-D-xylopyranosyloxy(1 -> 6)-beta-D-glucopyranosyloxy)phenyl ]-3,7-dioxabicyclo[3.3.0]octane (1), (1R,2R,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-[(3-methoxy-4-beta-D-xylopyranosyloxy(1 -> 6)-beta-D-glucopyranosyloxy)phenyl]-3,7-dioxabicyclo [3.3.0]octane (2), (1R,2R,5R,6S)-2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-beta-D-glucopyra-nosyloxy)phenyl-3,7-dioxabicyclo[3.3.0] octane (3), and (1R,2R,5R,6S)-2-(3,4-dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-dioxabicyclo[3.3.0] octane (4). Compounds 2 and 3 showed weak cytotoxicity against the HL-60 cell line with IC50 values of 61 and 99 mu M, respectively.
关键词	Lancea Tibetica Phrymaceae Cytotoxicity Furofurano Lignin Lantibeside Lantibetin
DOI	10.1055/s-2008-1081308
收录类别	SCI
语种	英语
WOS记录号	WOS:000260174300012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/23876
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Ocean Univ China, Chinese Minist Educ, Sch Med & Pharm, Key Lab Marine Drugs, Qingdao 266003, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming, Peoples R China
推荐引用方式 GB/T 7714	Li, Ting,Hao, Xiao-Jiang,Gu, Qian-Qun,et al. Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica[J]. PLANTA MEDICA,2008,74(11):1391-1396.
APA	Li, Ting,Hao, Xiao-Jiang,Gu, Qian-Qun,&Zhu, Wei-Ming.(2008).Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica.PLANTA MEDICA,74(11),1391-1396.
MLA	Li, Ting,et al."Minor Furofurano Lignans from the Tibetan Herb, Lancea tibetica".PLANTA MEDICA 74.11(2008):1391-1396.

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