Five ent-atisane diterpenoids, including three new ones, i.e., (16 alpha)-17-hydroxy-ent-atisan-19-oic acid methyl ester (1), (16 alpha)-17-dihydroxy-ent-atisan-19-oic acid methyl ester (2), (16a)-ent-atisan-16,17,19-triol (3), and two known compounds, i.e., 17-hydroxy-ent-atisan-19-oic acid (4), (16 alpha)-16,17-dihydroxy-ent-atisan-19-al (5), together with one known diterpene glycoside, i.e., sumogaside, two known triterpenes, i.e., germanicone and (3 beta)-beta-amyrin, three known phenolic compounds, i.e., (+)-gallocatechin, (+)-catechin, and gallic acid, and two known sterols, i.e., beta-sitosterol and daucosterol, were isolated from the callus cultures of Trewia nudiflora. Their structures were elucidated by spectroscopic analysis including 1D- and 2D-NMR experiments. No maytansinoids were isolated or detected by LC-ESI-MS in the extracts of the calli, which suggests that the callus cultures can not produce maytansinoids under these conditions.
1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
Recommended Citation:
Du, ZZ; Zhao, PJ; He, HP; Zhu, N; Hao, XJ; Shen, YM.The chemical constituents from the callus culture of Trewia nudiflora,HELVETICA CHIMICA ACTA,2005,88(9):2424-2429
