Natural inhibitors targeting osteoclast-mediated bone resorption

doi:10.1016/j.bmcl.2006.09.042

	Natural inhibitors targeting osteoclast-mediated bone resorption
	Zeng, Guang-Zhi ; Tan, Ning-Hua ; Hao, Xiao-Jiang; Mu, Quan-Zhang ; Li, Rong-Tao
	2006-12-15
发表期刊	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN	0960-894X
卷号	16 期号:24 页码:6178-6180
摘要	Human cathepsin K, matrix metalloproteinase 9, and alpha(V)beta(3) integrin are the key regulators in osteoclast-mediated bone resorption. In this paper, we found natural inhibitors 1-10 for them by enzyme inhibition assays. Inhibitors 1-7, 8-9, and 10 are novel inhibitors of human cathepsin K, matrix metalloproteinase 9, and alpha(V)beta(3), respectively. (c) 2006 Elsevier Ltd. All rights reserved.
关键词	Cathepsin k Matrix Metalloproteinase 9 Alpha v Beta(3) Natural Inhibitor Bone Resorption
学科领域	Chemistry ; Medicinal ; Chemistry ; Organic
DOI	10.1016/j.bmcl.2006.09.042
收录类别	SCI
语种	英语
WOS记录号	WOS:000242674100006
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/2133
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zeng, Guang-Zhi,Tan, Ning-Hua,Hao, Xiao-Jiang,et al. Natural inhibitors targeting osteoclast-mediated bone resorption[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2006,16(24):6178-6180.
APA	Zeng, Guang-Zhi,Tan, Ning-Hua,Hao, Xiao-Jiang,Mu, Quan-Zhang,&Li, Rong-Tao.(2006).Natural inhibitors targeting osteoclast-mediated bone resorption.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,16(24),6178-6180.
MLA	Zeng, Guang-Zhi,et al."Natural inhibitors targeting osteoclast-mediated bone resorption".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16.24(2006):6178-6180.

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