ent-kaurane diterpenoids from Isodon nervosus
Li, Li-Mei1,2; Li, Guo-You3; Ding, Li-Sheng3; Yang, Li-Bin1; Zhao, Yong1; Pu, Han-Xin1; Xiao, Wei-Lie1; Han, Quan-Bin1; Sun, Han-Dong1
2008-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号71期号:4页码:684-688
摘要A pentacyclic ent-kauranoid, nervonin A (1), with an unprecedented cyclobutane moiety in the structure, and nine other new ent-kaurane diterpenoids, nervonins B-J (2-10), along with 10 known ones (11-20), were isolated from Isodon nervosus. Their structures were elucidated by detailed spectroscopic analysis. All diterpenoids were assayed for their cytotoxicity against K562, A549, and HepG2 human cell lines. Compounds 2, 11, 16, 17, and 20 showed significant cytotoxicity.
关键词Rubescens Var.-taihangensis Kappa-b Activation Constituents Xerophilus Manner Cells
学科领域Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np800027a
收录类别SCI ; IC
语种英语
WOS记录号WOS:000255339100032
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/1907
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chengdu Med Coll, Ctr Sci Res, Chengdu 610083, Peoples R China
3.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China
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Li, Li-Mei,Li, Guo-You,Ding, Li-Sheng,et al. ent-kaurane diterpenoids from Isodon nervosus[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(4):684-688.
APA Li, Li-Mei.,Li, Guo-You.,Ding, Li-Sheng.,Yang, Li-Bin.,Zhao, Yong.,...&Sun, Han-Dong.(2008).ent-kaurane diterpenoids from Isodon nervosus.JOURNAL OF NATURAL PRODUCTS,71(4),684-688.
MLA Li, Li-Mei,et al."ent-kaurane diterpenoids from Isodon nervosus".JOURNAL OF NATURAL PRODUCTS 71.4(2008):684-688.
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