Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration

	Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration
	He,Ping ; Wang,Xiangfen ; Guo,Xiujie ; Ji,Yannan ; Zhou,Chuanqi ; Shen,Shigang ; Hu,Dongbao ; Yang,Xiaolong ; Luo,Duqiang ; Dukor,Rina ; Zhu,Huajie
通讯作者	Zhu,HJ (reprint author),Hebei Univ,Coll Pharm Sci,Chinese Ctr Chiral,Key Lab Med Chem & Mol Diagnost,Educ Minist China,Baoding 071002,Peoples R China. ; hjzhu@mail.kib.ac.cn
	2014
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	55 期号:18 页码:2965-2968
摘要	Bioactive natural product (+)-schizandrin was assigned as (7S,8S) using NMR. Recently, we obtained (+)schizandrin from TCM Schisandra sphenanthera Rehd. et Wils. Its planar structure was well established using NMR and HR-MS including the reported references. Its absolute configuration is assigned using vibrational circular dichroism (VCD). By careful VCD investigation of (75,8S) and (75,8R) using B3LYP/6-311+G(d) methods, absolute configuration of (+)-schizandrin is assigned as (7S,8R). Electronic circular dichroism (ECD) was used for the discussion too and it gave the same conclusion. (C) 2014 Elsevier Ltd. All rights reserved.
关键词	Absolute Configuration Schizandrin Vcd Ecd Dibenzocyclooctadiene Lignans (+)-isoschizandrin
学科领域	Chemistry
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/18111
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	He,Ping,Wang,Xiangfen,Guo,Xiujie,et al. Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration[J]. TETRAHEDRON LETTERS,2014,55(18):2965-2968.
APA	He,Ping.,Wang,Xiangfen.,Guo,Xiujie.,Ji,Yannan.,Zhou,Chuanqi.,...&Zhu,Huajie.(2014).Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration.TETRAHEDRON LETTERS,55(18),2965-2968.
MLA	He,Ping,et al."Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration".TETRAHEDRON LETTERS 55.18(2014):2965-2968.

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