| New acyclic diterpenoids from the fruits of Aphanamixis grandifolia and structure revision of nemoralisin B | |
Zhang, Hai-Yuan1,2; Yuan, Chun-Mao1; Cao, Ming-Ming1; Li, Xiao-Hui1; Li, Shun-Lin1; Zhang, Yu1 ; Hao, Xiao-Jiang1; He, Hong-Ping1,3
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| 通讯作者 | He,HP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; zhangyu@mail.kib.ac.cn ; hehongping@mail.kib.ac.cn |
| 2014-05-01 | |
| 发表期刊 | PHYTOCHEMISTRY LETTERS
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| ISSN | 1874-3900 |
| 卷号 | 8页码:81-85 |
| 摘要 | Four new acyclic diterpenoids (i.e., nemoralisin B (1) and nemoralisins H-J (2-4)) along with three known acyclic diterpenoids (i.e., nemoralisin, nemoralisin A, and nemoralisin D) were isolated from the fruits of Aphanamixis grandifolia. Their structures were determined by extensive spectroscopic studies using NMR spectroscopy and mass spectrometry. In addition, the structure of nemoralisin B has been revised from the previously reported a,beta-unsaturated delta-lactone structure to an a,beta-unsaturated glactone one. Nemoralisin J (4) exhibited moderate inhibitory activity against lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells with an IC50 value of 9.96 mu M. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| 关键词 | Aphanamixis Grandifolia Meliaceae Acyclic Diterpenoids Structure Revision |
| 学科领域 | Biochemistry & Molecular Biology ; Plant Sciences |
| DOI | 10.1016/j.phytol.2014.02.005 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000335743300018 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18108 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Yunnan Univ TCM, Fac Pharm, Kunming 650500, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hai-Yuan,Yuan, Chun-Mao,Cao, Ming-Ming,et al. New acyclic diterpenoids from the fruits of Aphanamixis grandifolia and structure revision of nemoralisin B[J]. PHYTOCHEMISTRY LETTERS,2014,8:81-85. |
| APA | Zhang, Hai-Yuan.,Yuan, Chun-Mao.,Cao, Ming-Ming.,Li, Xiao-Hui.,Li, Shun-Lin.,...&He, Hong-Ping.(2014).New acyclic diterpenoids from the fruits of Aphanamixis grandifolia and structure revision of nemoralisin B.PHYTOCHEMISTRY LETTERS,8,81-85. |
| MLA | Zhang, Hai-Yuan,et al."New acyclic diterpenoids from the fruits of Aphanamixis grandifolia and structure revision of nemoralisin B".PHYTOCHEMISTRY LETTERS 8(2014):81-85. |
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