Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii

	Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii
	Dong, Chuanfu 1,2; Liu, Lei 1,2; Li, Xiaonian 1; Guan, Zhengye 1,2; Luo, Huairong1 ; Wang, Yifen1
通讯作者	Wang, YF (reprint author), Chinese Acad Sci, Kunming Inst Bot, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China. ; wangyifen@mail.kib.ac.cn
	2013-03-01
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	79 期号:5 页码:338-347
摘要	Chemical investigation of the aerial parts of Illicium simonsii resulted in the isolation of nine new compounds, simonsols A-E (1-5), simonsins A-B (7-8), terpene-sesquineolignans, clovane-dunnianol (9), and p-menthadunnianol (10). Compound 5 was equilibrated with 7 as an inseparable mixture. The structures were elucidated by extensive NMR and MS analysis. Compounds 9, 10, and the mixture of 5 and 7 moderately inhibited acetylcholinesterase with IC50 values of 4.58 mu M, 6.55 mu M, and 10.34 mu M, respectively.
关键词	Illiciaceae Illicium Simonsii Sesquineolignans Terpene-sesquineolignans Anti-ache Activity
学科领域	Plant Sciences ; Pharmacology & Pharmacy
收录类别	SCI
语种	英语
WOS记录号	WOS:000316800900006
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/16467
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Grad Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Dong, Chuanfu,Liu, Lei,Li, Xiaonian,et al. Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii[J]. PLANTA MEDICA,2013,79(5):338-347.
APA	Dong, Chuanfu,Liu, Lei,Li, Xiaonian,Guan, Zhengye,Luo, Huairong,&Wang, Yifen.(2013).Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii.PLANTA MEDICA,79(5),338-347.
MLA	Dong, Chuanfu,et al."Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii".PLANTA MEDICA 79.5(2013):338-347.

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