Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola
Fang, LZ; Qing, C; Shao, HJ; Yang, YD; Dong, ZJ; Wang, F; Zhao, W; Yang, WQ; Liu, JK
2006-06-01
Source PublicationJOURNAL OF ANTIBIOTICS
ISSN0021-8820
Volume59Issue:6Pages:351-354
AbstractA fungal pigment, hypocrellin D (1), together with three known perylenequinone derivatives hypocrellin A (2), B (3) and C (4), was isolated from the fruiting bodies of Shiraia bambusicola. Its structure was elucidated on the basis of spectral data including 2D NMR experiments. Hypocrellin D (1) significantly inhibited the growth of tumor cell lines Bel-7721, A-549 and Anip-973 with IC50 values of 1.8, 8.8, 38.4, mu g/ml, respectively.
KeywordHypocrellin d Perylenequinone Shiraia Bambusicola Pigment Ascomycete Cytotoxicity
Subject AreaBiotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
Indexed BySCI
Language英语
WOS Research AreaBiotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS SubjectBiotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS IDWOS:000238785700004
Citation statistics
Cited Times:25[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/1569
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource W China, Kunming 650204, Peoples R China
2.Kunming Med Coll, Kunming 650031, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 1000439, Peoples R China
Recommended Citation
GB/T 7714
Fang, LZ,Qing, C,Shao, HJ,et al. Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola[J]. JOURNAL OF ANTIBIOTICS,2006,59(6):351-354.
APA Fang, LZ.,Qing, C.,Shao, HJ.,Yang, YD.,Dong, ZJ.,...&Liu, JK.(2006).Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola.JOURNAL OF ANTIBIOTICS,59(6),351-354.
MLA Fang, LZ,et al."Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola".JOURNAL OF ANTIBIOTICS 59.6(2006):351-354.
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