Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens | |
Liu, Hong-Xin2,3; Bi, Jun-Long1; Wang, Yue-Hu2; Gu, Wei2,3; Su, Yao4; Liu, Fang4; Yang, Shi-Xian4; Hu, Guang-Wan2; Luo, Ji-Feng2; Yin, Ge-Fen1; Long, Chun-Lin2,5 | |
Corresponding Author | Yin, GF (reprint author), Yunnan Agr Univ, Coll Anim Sci & Technol, Kunming 650201, Peoples R China. ; yingefen383@sohu.com ; long@mail.kib.ac.cn |
2012-07-01 | |
Source Publication | HELVETICA CHIMICA ACTA |
ISSN | 0018-019X |
Volume | 95Issue:7Pages:1231-1237 |
Abstract | Methyl pothoscandensate (1), a new molecular skeleton of ent-18(4?3)-abeokaurane, along with eight known compounds was isolated from the whole plant of Pothos scandens. The structure of the new compound was established by spectroscopic techniques and confirmed by single-crystal X-ray diffraction. The inhibitory activity of selected compounds against porcine respiratory and reproductive syndrome virus (PRRSV) was measured by the cytopathic effect (CPE) method. Compound 1 showed weak effect on PRRSV with an IC50 value of 40.3 +/- 8.3 mu M (TI=15.7). |
Keyword | Pothos Scandens Methyl Pothoscandensate Antiviral Activity X-ray Crystallography |
Subject Area | Chemistry, Multidisciplinary |
DOI | 10.1002/hlca.201200006 |
Indexed By | SCI ; IC |
Language | 英语 |
WOS ID | WOS:000306277000024 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.kib.ac.cn/handle/151853/15127 |
Collection | 资源植物与生物技术所级重点实验室 |
Affiliation | 1.Yunnan Agr Univ, Coll Anim Sci & Technol, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Yunnan Agr Univ, Coll Hort & Landscape, Kunming 650201, Peoples R China 5.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China |
Recommended Citation GB/T 7714 | Liu, Hong-Xin,Bi, Jun-Long,Wang, Yue-Hu,et al. Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens[J]. HELVETICA CHIMICA ACTA,2012,95(7):1231-1237. |
APA | Liu, Hong-Xin.,Bi, Jun-Long.,Wang, Yue-Hu.,Gu, Wei.,Su, Yao.,...&Long, Chun-Lin.(2012).Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens.HELVETICA CHIMICA ACTA,95(7),1231-1237. |
MLA | Liu, Hong-Xin,et al."Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens".HELVETICA CHIMICA ACTA 95.7(2012):1231-1237. |
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