Two new triterpenes from Neonaudea sessilifolia

	Two new triterpenes from Neonaudea sessilifolia
	Kang, WY ; Li, GH ; Hao, XJ
	2003-08-01
发表期刊	ACTA BOTANICA SINICA
卷号	45 期号:8 页码:1003-1007
摘要	Two new triterpenoids, 3 beta, 15 alpha, 21 beta, 23-tetrahydroxy-12-oleanen-28-oic acid (1), 3 beta, 6 alpha, 21 beta, 23-tetrahydroxy-12-oleanen-28-oic acid (2), together with seven known compounds, viz., paeonol (3), 3, 4-dihydroxybenzoic acid (4), scosoletin (5), anthraquinones chrysophanol (6), 4H-1-benzopyran-4-one, 5, 7-dihydroxy-2-methyl (7), beta-sitosterol (8) and stigmasterol glucoside (9) were isolated by the chromatography of the silica gel, RP-18 and Sephadex-LH 20 from the EtOAc extract of Neonauclea sessilifolia (Roxb.) Merr. (Rubiaceae). Their structures were elucidated based on spectral analysis including 1D-, 2D-NMR (HMQC, HMBC), IR and EIMS. Among them, compound 6 was shown to possess inhibitory activity on the growth of Mycobacterium tuberculosis (Zopf) Lehmann et Neumann with a minimum inhibitory amount of 25 mug, compounds 2 and 4 also showed weak inhibitory activities on the growteof M. tuberculosis.
关键词	Neonauclea Sessilifolia Mycobacterium Tuberculosis Triterpenes
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000184913500018
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/14571
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Yunnan Univ, Key Lab Microbial Fermentat Engn, Kunming 650091, Peoples R China
推荐引用方式 GB/T 7714	Kang, WY,Li, GH,Hao, XJ. Two new triterpenes from Neonaudea sessilifolia[J]. ACTA BOTANICA SINICA,2003,45(8):1003-1007.
APA	Kang, WY,Li, GH,&Hao, XJ.(2003).Two new triterpenes from Neonaudea sessilifolia.ACTA BOTANICA SINICA,45(8),1003-1007.
MLA	Kang, WY,et al."Two new triterpenes from Neonaudea sessilifolia".ACTA BOTANICA SINICA 45.8(2003):1003-1007.

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