CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS

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	CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS
	YUE, XF; HAN, JX; SHEN, ZM; YANG, WY; LU, LJ; LI, BJ; WANG, C; XU, XK
	1992-05-01
发表期刊	ACTA PHARMACOLOGICA SINICA
ISSN	0253-9756
卷号	13 期号:3 页码:252-255
摘要	Trewiasine (TWS) is a mytansinoid compound. It possessed a significant cytotoxic activity against various human cancer cell lines in vitro. U937 cells, which were more sensitive to the TWS, required TWS 1-mu-g . ml-1 to inhibit cell growth over 90% (P < 0.01). TWS also showed activities against murine tumors in vivo, such as the ascitic tumors S180, hepatoma, U14, and solid tumor Lewis lung carcinoma.
关键词	Trewiasine Maytansine Cultured Tumor Cells Experimental Neoplasms Phytogenic Antineoplastic Agents
学科领域	Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
收录类别	sci
语种	英语
WOS记录号	WOS:A1992HT97500016
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/14377
专题	离退休
推荐引用方式 GB/T 7714	YUE, XF,HAN, JX,SHEN, ZM,et al. CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS[J]. ACTA PHARMACOLOGICA SINICA,1992,13(3):252-255.
APA	YUE, XF.,HAN, JX.,SHEN, ZM.,YANG, WY.,LU, LJ.,...&XU, XK.(1992).CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS.ACTA PHARMACOLOGICA SINICA,13(3),252-255.
MLA	YUE, XF,et al."CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS".ACTA PHARMACOLOGICA SINICA 13.3(1992):252-255.