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CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS
YUE, XF; HAN, JX; SHEN, ZM; YANG, WY; LU, LJ; LI, BJ; WANG, C; XU, XK
1992-05-01
发表期刊ACTA PHARMACOLOGICA SINICA
ISSN0253-9756
卷号13期号:3页码:252-255
摘要Trewiasine (TWS) is a mytansinoid compound. It possessed a significant cytotoxic activity against various human cancer cell lines in vitro. U937 cells, which were more sensitive to the TWS, required TWS 1-mu-g . ml-1 to inhibit cell growth over 90% (P < 0.01). TWS also showed activities against murine tumors in vivo, such as the ascitic tumors S180, hepatoma, U14, and solid tumor Lewis lung carcinoma.
关键词Trewiasine Maytansine Cultured Tumor Cells Experimental Neoplasms Phytogenic Antineoplastic Agents
收录类别sci
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14377
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YUE, XF,HAN, JX,SHEN, ZM,et al. CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS[J]. ACTA PHARMACOLOGICA SINICA,1992,13(3):252-255.
APA YUE, XF.,HAN, JX.,SHEN, ZM.,YANG, WY.,LU, LJ.,...&XU, XK.(1992).CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS.ACTA PHARMACOLOGICA SINICA,13(3),252-255.
MLA YUE, XF,et al."CYTOTOXIC ACTIVITY OF TREWIASINE IN 4 HUMAN CANCER CELL-LINES AND 5 MURINE TUMORS".ACTA PHARMACOLOGICA SINICA 13.3(1992):252-255.
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