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A new ergostanol saponin from Dioscorea deltoidea Wall var. orbiculata
Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS
2002-09-01
发表期刊JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
卷号4期号:3页码:211-215
摘要From the fresh rhizomes of Dioscorea deltoidea Wall var. orbiculata, a novel ergostanol saponin, orbiculatoside A (1), was isolated and identified as 3-O-beta-D-glucopyranosyl-ergost-5-ene-3beta, 26-diol-26-O-beta-D-glucopyranosyl(1 --> 3)-[beta-D-glucopyranosyl(1 --> 2)-beta-D-glucupyranosyl(1 --> 6)]-beta-D-glucopyranoside by various NMR techniques in combination with chemical methods. The new saponin showed strong activity against Pyricularia oryzae, with a MMDC (minimum morphological deformation concentration) value of 28.04 mumol/l and was cytotoxic to cancer cell line K562, HCT-15, A549, HT1080, and A2780a in vitro.
关键词Dioscorea Deltoidea Wall Var. Orbiculata Orbiculatoside a Pyricularia Oryzae Cytotoxic
学科领域Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1080/10286020290024013
收录类别IC ; SCI
语种英语
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000176932100010
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14219
专题离退休
作者单位1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
2.Beijing Inst Biomed, Beijing 100091, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Shen, P,Wang, SL,Liu, XK,et al. A new ergostanol saponin from Dioscorea deltoidea Wall var. orbiculata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2002,4(3):211-215.
APA Shen, P,Wang, SL,Liu, XK,Yang, CR,Cai, B,&Yao, XS.(2002).A new ergostanol saponin from Dioscorea deltoidea Wall var. orbiculata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,4(3),211-215.
MLA Shen, P,et al."A new ergostanol saponin from Dioscorea deltoidea Wall var. orbiculata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 4.3(2002):211-215.
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