Chemical constituents of the suspension cell cultures of Maytenus hookeri

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	Chemical constituents of the suspension cell cultures of Maytenus hookeri
	Lu, CH ; Zhang, JX ; Gan, FY ; Shen, YM
	2002-05-01
发表期刊	ACTA BOTANICA SINICA
ISSN	0577-7496
卷号	44 期号:5 页码:603-610
摘要	Suspension cell cultures of Maytenus hookeri Loos. (Celastraceae) in SH media were established from the calli induced from the leaves and young steins of M. hookeri on MS media with the supplement of 2 mg/L 2,4-D and 0.1 mg/L KIN (kinetin). Ethyl acetate extract of the cultures showed inhibitory activities against Penicillium avellaneum UC-4376 which was sensitive to maytansinoids. Exhaustive isolation of natural products from a large scale of suspension cell cultures did not yield maytansine instead of affording nine compounds including one novel triterpenoid, named 2, 3-diacetoxyl maytenusone (1), and eight known ones including squalene (2), beta-sitosterol (3), 2', 3', 4-triacetyl-sitoindoside I (4), salaspermic acid (5), maytenonic acid (6), 2alpha-hydroxy-maytenonic acid (7), 6, 11,12-trihydroxy-8, 11, 13-abietrien-7-one (8) and 11, 12-dihydroxy-8, 11, 13-abietatrien-7-one (9) elucidated on the basis of 1D and 2D NMR data. The H-1-NMR and C-13-NMR assignments were made for 1, 5, 6 and 7, while the C-13-NMR assignments for 5 and 6 were revised. The chemical results suggested that the suspension cell cultures of M. hookeri did not produce maytansinoids under the reported experiment conditions.
关键词	Maytenus Hookeri Celastraceae Suspension Cell Cultures Maytansine 2 3-diacetoxyl Maytenusone
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000175739000018
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/14211
专题	离退休
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Key Lab Nat Prod Chem Guizhou Prov, Guiyang 550002, Peoples R China 3.Acad Sinica, Guiyang 550002, Peoples R China
推荐引用方式 GB/T 7714	Lu, CH,Zhang, JX,Gan, FY,et al. Chemical constituents of the suspension cell cultures of Maytenus hookeri[J]. ACTA BOTANICA SINICA,2002,44(5):603-610.
APA	Lu, CH,Zhang, JX,Gan, FY,&Shen, YM.(2002).Chemical constituents of the suspension cell cultures of Maytenus hookeri.ACTA BOTANICA SINICA,44(5),603-610.
MLA	Lu, CH,et al."Chemical constituents of the suspension cell cultures of Maytenus hookeri".ACTA BOTANICA SINICA 44.5(2002):603-610.

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