Cytotoxic diterpenoids from Isodon enanderianus

	Cytotoxic diterpenoids from Isodon enanderianus
	Xiang, W ; Na, Z ; Li, SH; Li, ML ; Li, RT ; Tian, QE ; Sun, HD
	2003-11-01
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	69 期号:11 页码:1031-1035
摘要	Five new ent-kaurane diterpenoids, enanderianins K-O (1-5), and one new ent-abietane diterpenoid, enanderianin P (6), together with five known ent-kaurane diterpenoids, rabdocoetsin A (7), rabdocoetsin B (8), rabdocoetsin D (9), megathyrin A (10), megathyrin B (11) were isolated from the aerial parts of Isodon enanderianus. Their structures were determined by spectral means. Some diterpenoids were tested for their cytotoxicity against the human tumor K562 cells. Compounds 1, 2, 6, 8, 9 showed significant inhibitory activities against K562 cells with IC50 values ranging from 0.13 to 0.87 mug/mL.
关键词	Isodon Enanderianus Labiatae Diterpenoids Ent-kaurane Ent-abietane Enanderianins K-p Cytotoxicity
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别	SCI
语种	英语
WOS记录号	WOS:000187741500012
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/13631
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Kunming Med Coll, Yunnan Phatmacol Lab Nat Prod, Kunming, Peoples R China
推荐引用方式 GB/T 7714	Xiang, W,Na, Z,Li, SH,et al. Cytotoxic diterpenoids from Isodon enanderianus[J]. PLANTA MEDICA,2003,69(11):1031-1035.
APA	Xiang, W.,Na, Z.,Li, SH.,Li, ML.,Li, RT.,...&Sun, HD.(2003).Cytotoxic diterpenoids from Isodon enanderianus.PLANTA MEDICA,69(11),1031-1035.
MLA	Xiang, W,et al."Cytotoxic diterpenoids from Isodon enanderianus".PLANTA MEDICA 69.11(2003):1031-1035.

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