Chemical constituents from the stem bark of Trewia nudiflora L. and their antioxidant activities
Kang, Qian-jin1,3; Yang, Xian-wen1,2; Wu, Shao-hua1; Ma, Yan-ling4; Li, Ling4; Shen, Yue-mao1
2008-03-01
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume74Issue:4Pages:445-448
AbstractThree new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4-O-beta-(6"-O-galloyl)-glucopyranoside (1), 4,4'-O-dimethylellagic acid 3-(2"-O-acetyl)-alpha-rhamnopyranoside (2), and ethyl O-beta-(6'-galloyl)-glucopyranoside (3), together with eleven known ones, were isolated from the stem bark of Trewia nudiflora. Their structures were elucidated by means of I D, 2 D NMR and HR-MS analyses. The antioxidant activities of these compounds were evaluated with the DPPH radical-scavenging assay. Compound 1 showed significant antioxidant activity. In addition, compounds 1, 2 and 3 rescued the H2O2-induced PC12 cell death at 0.4 mu M in the MTT assay.
KeywordTrewia Nudiflora Euphorbiaceae Stem Bark Antioxidant Activities
Subject AreaPlant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1055/s-2008-1034361
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000255365500015
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/13603
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Second Mil Med Univ, Sch Pharm, Dep Nat Prod Chem, Shanghai, Peoples R China
3.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China
4.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming, Peoples R China
Recommended Citation
GB/T 7714
Kang, Qian-jin,Yang, Xian-wen,Wu, Shao-hua,et al. Chemical constituents from the stem bark of Trewia nudiflora L. and their antioxidant activities[J]. PLANTA MEDICA,2008,74(4):445-448.
APA Kang, Qian-jin,Yang, Xian-wen,Wu, Shao-hua,Ma, Yan-ling,Li, Ling,&Shen, Yue-mao.(2008).Chemical constituents from the stem bark of Trewia nudiflora L. and their antioxidant activities.PLANTA MEDICA,74(4),445-448.
MLA Kang, Qian-jin,et al."Chemical constituents from the stem bark of Trewia nudiflora L. and their antioxidant activities".PLANTA MEDICA 74.4(2008):445-448.
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