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题名: Secondary metabolites from endophytic Streptomyces aureofaciens CMUAc130 and their antifungal activity
作者: Taechowisan, T ; Lu, CH ; Shen, YM ; Lumyong, S
刊名: MICROBIOLOGY-SGM
英文摘要: Streptomyces aureofaciens CMUAc130 was isolated from the root tissue of Zingiber officinale Rosc. (Zingiberaceae). It was an antagonist of Colletotrichum musae and Fusarium oxysporum, the causative agents of anthracnose of banana and wilt of wheat, respectively. Evidence for the in vitro antibiosis of S. aureofaciens CMUAc130 was demonstrated by the zone of fungal-growth inhibition. Microscopic observations showed thickness and bulbous structures at the edges of the inhibited fungal hyphae. The culture filtrate and crude extract from this strain were all inhibitory to tested phytopathogenic fungi. The major active ingredients from the culture filtrate of S. aureofaciens CMUAc130 were purified by silica gel-column chromatography and identified to be (i) 5,7-dimethoxy-4-p-methoxylphenylcoumarin and (ii) 5,7-dimethoxy-4-phenylcoumarin by NMR and mass-spectral data, respectively. Bioassay studies showed that compounds (i) and (ii) had antifungal activities against tested fungi, and their MICs were found to be 120 and 150 mu g ml(-1), respectively. This is the first report of compounds (i) and (ii) from micro-organisms as active ingredients for the control of phytopathogenic fungi.
出版日期: 2005
卷号: 151, 期号:Part 5, 页码:1691-1695
语种: 英语
收录类别: sci
学科分类: Microbiology
ISSN号: 1350-0872
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/13545
Appears in Collections:离退休_期刊论文

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Recommended Citation:
Taechowisan, T; Lu, CH; Shen, YM; Lumyong, S.Secondary metabolites from endophytic Streptomyces aureofaciens CMUAc130 and their antifungal activity,MICROBIOLOGY-SGM,2005,151(Part 5):1691-1695
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