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Steroidal saponins from rhizomes of Tupistra wattii Hook. f.
Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS
Corresponding Authoryaoxinsheng@hotmail.com
2003-03-01
Source PublicationCHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
Volume51Issue:3Pages:305-308
AbstractChemical examination of the fresh rhizomes of Tupistra wattii HOOK. f. led to the isolation of three new steroidal saponins, wattoside G (1), H (2), and 1 (3), together with one known steroidal saponin, (25S)-1beta,3beta,4beta-trihydroxyspirotan-5beta-yl-O-beta-D-glucopyranoside (4). The structures of 1-3 were established to be (25R)1beta,2beta,3beta,5beta-tetrahydroxyspirostan-4beta-yl-O-beta-D-xylopyranoside (1), (24S,25S)-24-[(beta-D-glucopyranosyl)oxy]-1beta,2beta,3beta,4beta,5beta,7beta-hexahydroxyspirostan-6-one (2), and (24S,25S)-1beta,3beta-dihydroxy-5beta-spirostan-24-yl-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (3) on the basis of detailed analyses of physical, chemical, and spectral data. The isolated compounds were evaluated for cytotoxic activity against the cancer cell line K562 in vitro.
KeywordTupistra Wattii Steroidal Saponin Wattoside g Wattoside h Wattoside i Cancer Cell Line K562
Subject AreaChemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
Indexed BySCI ; IC
Language英语
WOS Research AreaPharmacology & Pharmacy ; Chemistry
WOS SubjectChemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS IDWOS:000181234600014
Citation statistics
Cited Times:16[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/13529
Collection离退休
Affiliation1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
2.Beijing Inst Biomed, Beijing 100091, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
Recommended Citation
GB/T 7714
Shen, P,Wang, SL,Liu, XK,et al. Steroidal saponins from rhizomes of Tupistra wattii Hook. f.[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2003,51(3):305-308.
APA Shen, P,Wang, SL,Liu, XK,Yang, CR,Cai, B,&Yao, XS.(2003).Steroidal saponins from rhizomes of Tupistra wattii Hook. f..CHEMICAL & PHARMACEUTICAL BULLETIN,51(3),305-308.
MLA Shen, P,et al."Steroidal saponins from rhizomes of Tupistra wattii Hook. f.".CHEMICAL & PHARMACEUTICAL BULLETIN 51.3(2003):305-308.
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