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题名: Steroidal saponins from rhizomes of Tupistra wattii Hook. f.
作者: Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
关键词: Tupistra wattii ; steroidal saponin ; wattoside G ; wattoside H ; wattoside I ; cancer cell line K562
英文摘要: Chemical examination of the fresh rhizomes of Tupistra wattii HOOK. f. led to the isolation of three new steroidal saponins, wattoside G (1), H (2), and 1 (3), together with one known steroidal saponin, (25S)-1beta,3beta,4beta-trihydroxyspirotan-5beta-yl-O-beta-D-glucopyranoside (4). The structures of 1-3 were established to be (25R)1beta,2beta,3beta,5beta-tetrahydroxyspirostan-4beta-yl-O-beta-D-xylopyranoside (1), (24S,25S)-24-[(beta-D-glucopyranosyl)oxy]-1beta,2beta,3beta,4beta,5beta,7beta-hexahydroxyspirostan-6-one (2), and (24S,25S)-1beta,3beta-dihydroxy-5beta-spirostan-24-yl-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (3) on the basis of detailed analyses of physical, chemical, and spectral data. The isolated compounds were evaluated for cytotoxic activity against the cancer cell line K562 in vitro.
出版日期: 2003-03-01
卷号: 51, 期号:3, 页码:305-308
语种: 英语
收录类别: SCI ; IC
学科分类: Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy
ISSN号: 0009-2363
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/13529
Appears in Collections:离退休_期刊论文

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作者单位: 1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
2.Beijing Inst Biomed, Beijing 100091, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China

Recommended Citation:
Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS.Steroidal saponins from rhizomes of Tupistra wattii Hook. f.,CHEMICAL & PHARMACEUTICAL BULLETIN,2003,51(3):305-308
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