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Steroidal saponins from rhizomes of Tupistra wattii Hook. f.
Shen, P; Wang, SL; Liu, XK; Yang, CR; Cai, B; Yao, XS
2003-03-01
发表期刊CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN0009-2363
卷号51期号:3页码:305-308
摘要Chemical examination of the fresh rhizomes of Tupistra wattii HOOK. f. led to the isolation of three new steroidal saponins, wattoside G (1), H (2), and 1 (3), together with one known steroidal saponin, (25S)-1beta,3beta,4beta-trihydroxyspirotan-5beta-yl-O-beta-D-glucopyranoside (4). The structures of 1-3 were established to be (25R)1beta,2beta,3beta,5beta-tetrahydroxyspirostan-4beta-yl-O-beta-D-xylopyranoside (1), (24S,25S)-24-[(beta-D-glucopyranosyl)oxy]-1beta,2beta,3beta,4beta,5beta,7beta-hexahydroxyspirostan-6-one (2), and (24S,25S)-1beta,3beta-dihydroxy-5beta-spirostan-24-yl-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (3) on the basis of detailed analyses of physical, chemical, and spectral data. The isolated compounds were evaluated for cytotoxic activity against the cancer cell line K562 in vitro.
关键词Tupistra Wattii Steroidal Saponin Wattoside g Wattoside h Wattoside i Cancer Cell Line K562
学科领域Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
收录类别SCI ; IC
语种英语
WOS研究方向Pharmacology & Pharmacy ; Chemistry
WOS类目Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS记录号WOS:000181234600014
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13529
专题离退休
作者单位1.Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Peoples R China
2.Beijing Inst Biomed, Beijing 100091, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Shen, P,Wang, SL,Liu, XK,et al. Steroidal saponins from rhizomes of Tupistra wattii Hook. f.[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2003,51(3):305-308.
APA Shen, P,Wang, SL,Liu, XK,Yang, CR,Cai, B,&Yao, XS.(2003).Steroidal saponins from rhizomes of Tupistra wattii Hook. f..CHEMICAL & PHARMACEUTICAL BULLETIN,51(3),305-308.
MLA Shen, P,et al."Steroidal saponins from rhizomes of Tupistra wattii Hook. f.".CHEMICAL & PHARMACEUTICAL BULLETIN 51.3(2003):305-308.
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