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Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
作者:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
浏览  |  Adobe PDF(1230Kb)  |  收藏  |  浏览/下载：104/52  |  提交时间：2022/04/02
pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：186/65  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：235/83  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Metabolic profiling of myrislignan by UPLC-ESI-QTOFMS-based metabolomics 期刊论文
RSC ADVANCES, 2017, 卷号: 7, 期号: 64, 页码: 40131-40140
作者:  Yang, Xiao-Nan;  Lv, Qian-Qian;  Zhao, Qi;  Li, Xin-Mei;  Yan, Dong-Mei;  Yang, Xiu-Wei;  Li, Fei
浏览  |  Adobe PDF(956Kb)  |  收藏  |  浏览/下载：205/64  |  提交时间：2017/10/23
Myristica-fragrans  In-vitro  Liver-microsomes  Neolignans  Extract  Lignans  Pharmacokinetics  Identification  Noscapine  Reveals  
High-performance liquid chromatographic assay for theactive saponins from Panax notoginseng in rat tissues 期刊论文
Biomed. Chromatogr., 2006, 卷号: 20, 期号: 0, 页码: 327–335
作者:  Lie Li;  Yu-Xin Sheng;  in-Lan Zhang;  Shan-Shan Wang;  De-An Guo
Adobe PDF(350Kb)  |  收藏  |  浏览/下载：40/1  |  提交时间：2017/07/24
Panax Notoginseng  Ginsenosides  Tissue Distribution  Pharmacokinetics  
HPLC determination of four active saponins from Panaxnotoginseng in rat serum and its application topharmacokinetic studies 期刊论文
Biomed. Chromatogr., 2004, 卷号: 18, 期号: 0, 页码: 849–856
作者:  Lie Li;  Yuxin Sheng;  Jinlan Zhang;  Chuanshe Wang;  Dean Guo
Adobe PDF(249Kb)  |  收藏  |  浏览/下载：33/0  |  提交时间：2017/07/24
Ginsenosides  Notoginsenoside  Panax Notoginseng  Rat Serum  Hplc  Pharmacokinetics