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PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
Favorite  |  View/Download:11/0  |  Submit date:2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
Authors:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
Favorite  |  View/Download:3/0  |  Submit date:2022/04/02
bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Chemical constituents of Euphorbia peplus 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2021, 卷号: 98, 页码: 104307
Authors:  Min,Xiao-Yan;  Chen,Yan-Ni;  Li,Dong-Mei;  Mu,Qiu-Yan;  Zhang,Zun-Ting;  Fang,Xin
Favorite  |  View/Download:6/0  |  Submit date:2022/04/02
Euphorbia peplus  Diterpene  Bisnorsesquiterpene  Monoterpene  Chemotaxonomy  JATROPHANE DITERPENOIDS  GUIDED ISOLATION  LOLIOLIDE  LATEX  
Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 166, 页码: 11
Authors:  Fan, Min;  Luo, Dan;  Peng, Li-Yan;  Li, Xiao-Nian;  Wu, Xing-De;  Ji, Xu;  Zhao, Qin-Shi
View  |  Adobe PDF(1457Kb)  |  Favorite  |  View/Download:107/21  |  Submit date:2019/10/28
Salvia hispanica L. (Lamiaceae)  Chia  Neo-clerodane diterpenoids  Hispanins A-J  Single crystal X-ray diffraction analysis  Cardioprotective effects  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:102/6  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
Authors:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
View  |  Adobe PDF(1093Kb)  |  Favorite  |  View/Download:101/13  |  Submit date:2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
Authors:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
View  |  Adobe PDF(2607Kb)  |  Favorite  |  View/Download:169/24  |  Submit date:2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Miscellaneous notes on Begonia medogensis (Begoniaceae) 期刊论文
PHYTOTAXA, 2018, 卷号: 381, 期号: 1, 页码: 100-106
Authors:  Chen, Wen-Hong;  Tian, Dai-Ke;  Radbouchoom, Sirilak;  Xiao, Yan;  Cong, Yi-Yan;  Guo, Shi-Wei;  Shui, Yu-Min
View  |  Adobe PDF(2159Kb)  |  Favorite  |  View/Download:97/28  |  Submit date:2018/12/27
Begonia sect. Platycentrum  China  Medog county  Misidentification  Supplementary description  Tibet  
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
Authors:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
Favorite  |  View/Download:145/0  |  Submit date:2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase