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Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载:285/66  |  提交时间:2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11, 页码: 2966-2973
作者:  Ni, Guanghui;  Li, Zhiyuan;  Liang, Kangjiang;  Wu, Ting;  De Libero, Gennaro;  Xia, Chengfeng
Adobe PDF(861Kb)  |  收藏  |  浏览/下载:227/63  |  提交时间:2014/06/23
Nkt Cells  Antigen  Lysophospholipids  Sar  
Palladium-Catalyzed Unactivated C(sp(3))-H Bond Activation and intramolecular Amination of Carboxamides: A New Approach to beta-Lactams 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 480-483
作者:  Sun, Wen-Wu;  Cao, Pei;  Mei, Ren-Qiang;  Li, Yue;  Ma, Yuan-Liang;  Wu, Bin
Adobe PDF(326Kb)  |  收藏  |  浏览/下载:597/56  |  提交时间:2014/04/09
C-h Activation  Carbon-hydrogen Bonds  Side-chain Sar  Acid Derivatives  Directing Group  Arylation  Functionalization  Inhibitors  Gamma  Construction  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(555Kb)  |  收藏  |  浏览/下载:494/101  |  提交时间:2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
Anti-Tobacco Mosaic Virus (TMV) Quassinoids from Brucea javanica (L.) Merr. 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 卷号: 58, 期号: 3, 页码: 1572-1577
作者:  Yan, Xiao-Hui;  Chen, Jia;  Di, Ying-Tong;  Fang, Xin;  Dong, Jia-Hong;  Sang, Peng;  Wang, Yue-Hu;  He, Hong-Ping;  Zhang, Zhong-Kai;  Hao, Xiao-Jiang
Adobe PDF(1644Kb)  |  收藏  |  浏览/下载:559/226  |  提交时间:2012/03/21
Tobacco Mosaic Virus (Tmv)  Brucea Javanica (L.) Merr.  Quassinoids  Structure-activity Relationship (Sar)  
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 9, 页码: 4860-4871
作者:  Zhao, Yu;  Guo, Na;  Lou, Li-Guang;  Cong, Yu-Wen;  Peng, Li-Yan;  Zhao, Qin-Shi
Adobe PDF(416Kb)  |  收藏  |  浏览/下载:291/114  |  提交时间:2011/11/24
Derivatives Of Taxchinin a And Brevifoliol  Synthesis  Cytotoxicity  Sar  
Synthesis and cytotoxicity of some new eriocalyxin B derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 卷号: 42, 期号: 4, 页码: 494-502
作者:  Zhao, Yu;  Niu, Xue-Mei;  Qian, Li-Ping;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Sun, Han-Dong
Adobe PDF(329Kb)  |  收藏  |  浏览/下载:308/114  |  提交时间:2011/11/24
Eriocalyxin b  Synthesis  Cytotoxicity  Sar  
Synthesis of cytotoxic sinapyl alcohol derivatives fromLigularia nelumbifolia 期刊论文
CHINESE CHEMICAL LETTERS, 2002, 卷号: 13, 期号: 3, 页码: 201-204
作者:  Zhao, Y;  Lu, W;  Hao, XJ;  Cai, JC;  Yu, H;  Sevenet, T;  Gueritte, F
Adobe PDF(33Kb)  |  收藏  |  浏览/下载:2514/306  |  提交时间:2012/03/21
Natural Products  Cytotoxicity  Total Synthesis  Sar  Pharmaceutical Chemistry  Sinapyl Alcohol Derivatives