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Polycyclic polyprenylated acylphloroglucinols with immunosuppressive activity from Hypericum perforatum and absolute configurations assignment of previously reported analogues 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105144
作者:  Guo,Yi;  Cao,Yunfang;  Qi,Changxing;  Tong,Qingyi;  Chen,Chunmei;  Yang,Jing;  Zhu,Hucheng;  Zhang,Yonghui
收藏  |  浏览/下载：54/0  |  提交时间：2022/04/02
Hypericum perforatum  Polycyclic polyprenylated acylphloroglucinols  Configuration assignment  Immunosuppressive activity  Neuroprotective activity  ST-JOHNS-WORT  PHLOROGLUCINOL DERIVATIVES  HYPERFORIN  INHIBITION  DEPRESSION  SKELETON  L.  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
作者:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
收藏  |  浏览/下载：44/0  |  提交时间：2022/04/02
AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU  
One new nucleoside and three furanpentanone derivatives from the aerial part of Rubia cordifolia L 期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 125-128
作者:  He,Dong-Bing;  Bai,Xue;  Ma,Yu-Han;  Qin,Hai-Jun;  Wu,Yi-Bing;  Lv,Dong-Jin;  Mei,Ren-Qiang
收藏  |  浏览/下载：50/0  |  提交时间：2022/04/02
Rubia cordifolia  Secondary metabolites  NO production inhibition  A-C  ROOTS  ANTHRAQUINONES  CYTOTOXICITY  CONSTITUENTS  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
作者:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
收藏  |  浏览/下载：38/0  |  提交时间：2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Identification of Bioactive Phytochemicals from Six Plants: Mechanistic Insights into the Inhibition of Rumen Protozoa, Ammoniagenesis, and alpha-Glucosidase 期刊论文
BIOLOGY-BASEL, 2021, 卷号: 10, 期号: 10, 页码: 1055
作者:  Ayemele,Aurele Gnetegha;  Ma,Lu;  Li,Xiumei;  Yang,Peilong;  Xu,Jianchu;  Yu,Zhongtang;  Bu,Dengpan
收藏  |  浏览/下载：39/0  |  提交时间：2022/04/02
bioactive phytochemicals  feed efficiency  microbial alpha-glucosidase  protozoa inhibition  SUBACUTE RUMINAL ACIDOSIS  ENTODINIUM-CAUDATUM  L. LEAVES  FERMENTATION  PERFORMANCE  GLYCOSIDES  ACARBOSE  GROWTH  
Five new secondary metabolites from the fungus Phomopsis asparagi 期刊论文
FITOTERAPIA, 2021, 卷号: 150, 页码: 104840
作者:  Zhou,Peng;  Yan,Shan;  Lu,Yuanyuan;  Li,Xiao-Nian;  Zhang,Mi;  Li,Qin;  Chen,Xia;  Wang,Jianping;  Zhu,Hucheng;  Chen,Chunmei;  Zhang,Yonghui
收藏  |  浏览/下载：44/0  |  提交时间：2022/04/02
Phomopsis asparagi  Diphenylcyclopentenone  Diketopiperazine  A-glucosidase inhibition  ASPERGILLUS-FUMIGATUS  STEM BLIGHT  DERIVATIVES  INHIBITORS  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载：39/0  |  提交时间：2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：98/49  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
作者:  Lin,Lisha;  Yang,Lian;  Chen,Jun;  Zhou,Lutan;  Li,Sujuan;  Gao,Na;  Zhao,Jinhua
Adobe PDF(3733Kb)  |  收藏  |  浏览/下载：42/14  |  提交时间：2022/04/02
Aggregation  fucosylated glycosaminoglycan  human platelets  secretion  alpha(IIb beta 3)  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  INTEGRIN ALPHA(IIB)BETA(3)  ACTIVATION  AGGLUTINATION  RECEPTOR  ADP  INHIBITION  GENERATION  MECHANISM  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：86/24  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN