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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：279/35  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death 期刊论文
PROTEIN & CELL, 2018, 卷号: 9, 期号: 12, 页码: 1013-1026
作者:  Li, Yang;  Zhang, Yu;  Gan, Qiwen;  Xu, Meng;  Ding, Xiao;  Tang, Guihua;  Liang, Jingjing;  Liu, Kai;  Liu, Xuezhao;  Wang, Xin;  Guo, Lingli;  Gao, Zhiyang;  Hao, Xiaojiang;  Yang, Chonglin
收藏  |  浏览/下载：88/0  |  提交时间：2019/03/29
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death 期刊论文
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT, 2018, 卷号: 54, 期号: 6, 页码: 606-611
作者:  Li, Yang;  Zhang, Yu;  Gan, Qiwen;  Xu, Meng;  Ding, Xiao;  Tang, Guihua;  Liang, Jingjing;  Liu, Kai;  Liu, Xuezhao;  Wang, Xin;  Guo, Lingli;  Gao, Zhiyang;  Hao, Xiaojiang;  Yang, Chonglin
收藏  |  浏览/下载：125/0  |  提交时间：2018/12/27
Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforata 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 19, 页码: 5592-5595
作者:  Fang, Xin;  Di, Ying Tong;  Zhang, Yu;  Xu, Zhi Ping;  Lu, Yang;  Chen, Qian Qian;  Zheng, Qi Tai;  Hao, Xiao Jiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(931Kb)  |  收藏  |  浏览/下载：278/96  |  提交时间：2015/07/20
Biosynthetic Pathways  Insecticidal Activity  Natural Products  Nicotinic Acetylcholine Receptors  Structure Elucidation  
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(418Kb)  |  收藏  |  浏览/下载：132/47  |  提交时间：2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Three New Indole Alkaloids from Trigonostemon Iii 期刊论文
ORGANIC LETTERS, 2010, 卷号: 12, 期号: 10, 页码: 2370-2373
作者:  Tan, Cheng-Jian;  Di, Ying-Tong;  Wang, Yue-Hu;  Zhang, Yu;  Si, Yi-Kang;  Zhang, Qiang;  Gao, Suo;  Hu, Xu-Jia;  Fang, Xin;  Li, Shi-Fei;  Hao, Xiao-Jiang
Adobe PDF(181Kb)  |  收藏  |  浏览/下载：354/130  |  提交时间：2012/03/21
Density-functional Theory  Reidioides  Daphnane  Rediocide  Roots  Plant