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Anti-Hepatitis B Virus Active Lactones from the Traditional Chinese Herb: Swertia mileensis 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 卷号: 17, 期号: 14, 页码: 3893-3903
作者:  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Guo, Rui-Hua;  Zhou, Jun;  Shen, Yong;  Zuo, Ai-Xue;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：380/123  |  提交时间：2012/04/10
Antiviral Agents  Biosynthesis  Fused-ring Systems  Hepatitis b Virus  Natural Products  Swerilactones H-k  Swertia Mileensis  
Synthesis and biological assay of 4-aryl-6-chloro-quinoline derivatives as novel non-nucleoside anti-HBV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 4, 页码: 1400-1408
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Wang, Li-Jun;  Geng, Chang-An;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(951Kb)  |  收藏  |  浏览/下载：442/140  |  提交时间：2012/04/10
Hepatitis b Virus  4-aryl-6-chloro-quinoline  Derivatives  Synthesis  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：343/88  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Swerilactones E-G, three unusual lactones from Swertia mileensis 期刊论文
TETRAHEDRON LETTERS, 2010, 卷号: 51, 期号: 18, 页码: 2483-2485
作者:  Geng, Chang-An;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Jiang, Zhi-Yong;  Luo, Jie;  Zhou, Jun;  Wang, Hong-Ling;  Chen, Ji-Jun
Adobe PDF(414Kb)  |  收藏  |  浏览/下载：318/137  |  提交时间：2012/03/21
Swertia Mileensis  Swerilactones E-g  Secoiridoid Aglycone  Anti Hbv Activity  
Anti-HBV agents. Part 3: Preliminary structure-activity relationships of tetra-acylalisol A derivatives as potent hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 23, 页码: 6659-6665
作者:  Zhang, Quan;  Jiang, Zhi-Yong;  Luo, Jie;  Ma, Yun-Bao;  Liu, Ji-Feng;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Zhou, Jun;  Niu, Wei;  Du, Fei-Fei;  Li, Li;  Li, Chuan;  Chen, Ji-Jun
Adobe PDF(2076Kb)  |  收藏  |  浏览/下载：479/126  |  提交时间：2012/03/21
Anti-hbv Activity  Protostane-type Triterpene  Alisol a  Derivatives  Chemical Modification  
Swerilactones C and D, anti-HBV New Lactones from a Traditional Chinese Herb: Swertia mileensis 期刊论文
ORGANIC LETTERS, 2009, 卷号: 11, 期号: 21, 页码: 4838-4841
作者:  Geng, Chang-An;  Zhang, Xue-Mei;  Shen, Yong;  Zuo, Ai-Xue;  Liu, Ji-Feng;  Ma, Yun-Bao;  Luo, Jia;  Zhou, Jun;  Jiang, Zhi-yong;  Chen, Ji-Jun
Adobe PDF(200Kb)  |  收藏  |  浏览/下载：257/47  |  提交时间：2012/03/21
Hepatitis-b-virus  Iridoids  
Swerilactones A and B, Anti-HBV New Lactones from a Tradtional Chinese Herb: Swertia mileensis as a Treatment for Viral Hepatitis 期刊论文
ORGANIC LETTERS, 2009, 卷号: 11, 期号: 18, 页码: 4120-4123
作者:  Geng, Chang-An;  Jiang, Zhi-Yong;  Ma, Yun-Bao;  Luo, Jie;  Zhang, Xue-Mei;  Wang, Hong-Ling;  Shen, Yong;  Zuo, Ai-Xue;  Zhou, Jun;  Chen, Ji-Jun
Adobe PDF(203Kb)  |  收藏  |  浏览/下载：492/240  |  提交时间：2012/03/21
Lamivudine Therapy  Virus  Alkaloids  Constituents  
Anti-HBV agents. Part 2: Synthesis and in vitro anti-hepatitis B virus activities of alisol A derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 8, 页码: 2148-2153
作者:  Zhang, Quan;  Jiang, Zhi-Yong;  Luo, Jie;  Liu, Ji-Feng;  Ma, Yun-Bao;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Zhou, Jun;  Chen, Ji-Jun
Adobe PDF(2279Kb)  |  收藏  |  浏览/下载：351/110  |  提交时间：2011/12/19
Anti-hbv Activity  Protostane-type Triterpene  Alisol a  Derivatives  Chemical Modification  
抗乙型肝炎药物组合物,其制备方法及其在制备药物中的应用 专利
申请日期: 2008-10-09, 公开日期: 2012-09-05
发明人:  陈纪军;  张泉;  江志勇;  罗杰;  马云保;  张雪梅;  周俊;  沈勇;  左爱学
收藏  |  浏览/下载：54/0  |  提交时间：2018/05/10
Anti-HBV agents. Part 1: Synthesis of alisol A derivatives: A new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 卷号: 18, 期号: 16, 页码: 4647-4650
作者:  Zhang, Quan;  Jiang, Zhi-Yong;  Luo, Jie;  Cheng, Pi;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Zhang, Feng-Xue;  Zhou, Jun;  Chen, Ji-Jun
Adobe PDF(173Kb)  |  收藏  |  浏览/下载：236/74  |  提交时间：2011/11/24
Anti-hbv Activity  Alisol a  Derivatives  Synthesis