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Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Zhou, Bei;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1438Kb)  |  收藏  |  浏览/下载：1361/789  |  提交时间：2016/01/19
Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 3, 页码: 1599-1611
作者:  Wan, Wei-Chao;  Chen, Wen;  Liu, Lan-Xiang;  Li, Yan;  Yang, Li-Juan;  Deng, Xiao-Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(509Kb)  |  收藏  |  浏览/下载：765/518  |  提交时间：2014/04/09
Hybrid Compound  Benzofuran  Imidazole  Cytotoxic Activity  Structure-activity Relationships  Molecular Docking  
Design, synthesis and antitumor activity of novel 8-substituted 2,3,5,6-tetrahydrobenzo[1,2-b:4, 5-b'] difuran imidazolium salt derivatives 期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 31, 页码: 16312-16319
作者:  Sun, Cheng-Jun;  Chen, Wen;  Li, Yan;  Liu, Lan-Xiang;  Wang, Xue-Quan;  Li, Li-Juan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：198/20  |  提交时间：2014/06/23
Hybrid Compounds  Cytotoxic Activities  Natural-products  Drug Discovery  Analogs  Dihydrobenzofuran  Cycloaddition  Benzofurans  Iodides  Trans  
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Yan, Ju-Ming;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Zhou, Bei;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(3339Kb)  |  收藏  |  浏览/下载：316/136  |  提交时间：2013/10/16
Hybrid Compound  Imidazole  Dibenzo[b  Antitumor Activities  d]Furan  Structure-activity Relationships  
Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 111-121
作者:  Wang, Xue-Quan;  Liu, Lan-Xiang;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Li, Liang;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(4369Kb)  |  收藏  |  浏览/下载：274/89  |  提交时间：2013/07/24
Hybrid Compound  2-benzylbenzofuran  Imidazole  Cytotoxic Activities  Structure-activity Relationships  
DAPK1 mediates the G1 phase arrest in human nasopharyngeal carcinoma cells induced by grifolin, a potential antitumor natural product 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 卷号: 670, 期号: 2-3, 页码: 427-434
作者:  Luo, Xiang-jian;  Li, Wei;  Yang, Li-fang;  Yu, Xin-fang;  Xiao, Lan-bo;  Tang, Min;  Dong, Xin;  Deng, Qi-pan;  Bode, Ann M.;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1137Kb)  |  收藏  |  浏览/下载：457/141  |  提交时间：2012/04/10
Grifolin  Dapk1  Cell Cycle  P21  Erk1/2  Npc  Mushroom  
Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells 期刊论文
EUROPEAN JOURNAL OF CANCER, 2011, 卷号: 47, 期号: 2, 页码: 316-325
作者:  Luo, Xiang-jian;  Li, Li-li;  Deng, Qi-pan;  Yu, Xin-fang;  Yang, Li-fang;  Luo, Fei-jun;  Xiao, Lan-bo;  Chen, Xiao-yan;  Ye, Mao;  Liu, Ji-kai;  Cao, Ya
Adobe PDF(1466Kb)  |  收藏  |  浏览/下载：533/164  |  提交时间：2012/04/10
Grifolin  Mushroom  Dapk1  P53  Apoptosis