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Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：290/72  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载：347/129  |  提交时间：2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents  
Synthesis of hemslecin A derivatives: A new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 5, 页码: 1201-1205
作者:  Guo, Rui-Hua;  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Quan;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhang, Rong-Ping;  Chen, Ji-Jun
浏览  |  Adobe PDF(460Kb)  |  收藏  |  浏览/下载：378/92  |  提交时间：2013/03/18
Hemslecin a  Derivatives  Hepatitis b Virus  
Synthesis, structure-activity relationships and biological evaluation of caudatin derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 9, 页码: 2877-2888
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Chen, Hao;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(2590Kb)  |  收藏  |  浏览/下载：349/121  |  提交时间：2012/06/07
Synthesis  Caudatin Derivatives  Anti-hbv Activity  Structure-activity Relationships  
Anti-Hepatitis B Virus Active Lactones from the Traditional Chinese Herb: Swertia mileensis 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 卷号: 17, 期号: 14, 页码: 3893-3903
作者:  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Guo, Rui-Hua;  Zhou, Jun;  Shen, Yong;  Zuo, Ai-Xue;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：378/122  |  提交时间：2012/04/10
Antiviral Agents  Biosynthesis  Fused-ring Systems  Hepatitis b Virus  Natural Products  Swerilactones H-k  Swertia Mileensis  
Synthesis and biological assay of 4-aryl-6-chloro-quinoline derivatives as novel non-nucleoside anti-HBV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 4, 页码: 1400-1408
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Wang, Li-Jun;  Geng, Chang-An;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(951Kb)  |  收藏  |  浏览/下载：438/137  |  提交时间：2012/04/10
Hepatitis b Virus  4-aryl-6-chloro-quinoline  Derivatives  Synthesis  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：338/88  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Anti-HBV agents. Part 3: Preliminary structure-activity relationships of tetra-acylalisol A derivatives as potent hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 23, 页码: 6659-6665
作者:  Zhang, Quan;  Jiang, Zhi-Yong;  Luo, Jie;  Ma, Yun-Bao;  Liu, Ji-Feng;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Zhou, Jun;  Niu, Wei;  Du, Fei-Fei;  Li, Li;  Li, Chuan;  Chen, Ji-Jun
Adobe PDF(2076Kb)  |  收藏  |  浏览/下载：477/126  |  提交时间：2012/03/21
Anti-hbv Activity  Protostane-type Triterpene  Alisol a  Derivatives  Chemical Modification