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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
作者:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
收藏  |  浏览/下载：51/0  |  提交时间：2022/04/02
Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
作者:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
收藏  |  浏览/下载：60/0  |  提交时间：2022/04/02
antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：129/40  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Anti-microbial Effects In Vitro and In Vivo of Alstonia scholaris 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 127-135
作者:  Zhao,Yun-Li;  Gou,Zhong-Ping;  Shang,Jian-Hua;  Li,Wan-Yi;  Kuang,Yu;  Li,Ming-Yuan;  Luo,Xiao-Dong
浏览  |  Adobe PDF(958Kb)  |  收藏  |  浏览/下载：87/28  |  提交时间：2022/04/02
Antioxidant and Cytoprotective Effects of New Diarylheptanoids from Rhynchanthus beesianus 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 22, 页码: 6229-6239
作者:  Zhu,Pei-Feng;  Cheng,Gui-Guang;  Zhao,Lan-Qin;  Khan,Afsar;  Yang,Xing-Wei;  Zhang,Bu-Yun;  Li,Meng-Cheng;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2113Kb)  |  收藏  |  浏览/下载：82/28  |  提交时间：2022/04/02
Rhynchanthus beesianus  diarylheptanoid  antioxidant activity  intracellular reactive oxygen species  cell apoptosis  GINGER ZINGIBER-OFFICINALE  PC12 CELLS  RHIZOMES  NEUROPROTECTION  ACTIVATION  ENZYMES  L.  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(5546Kb)  |  收藏  |  浏览/下载：104/43  |  提交时间：2022/04/02
Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：137/80  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
作者:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1568Kb)  |  收藏  |  浏览/下载：57/14  |  提交时间：2022/04/02
SKELETONS  
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267, 页码: 113506
作者:  Zhao,Yun-Li;  Pu,Shi-Biao;  Qi,Yan;  Wu,Bai-Fen;  Shang,Jian-Hua;  Liu,Ya-Ping;  Hu,Di;  Luo,Xiao-Dong
浏览  |  Adobe PDF(9993Kb)  |  收藏  |  浏览/下载：64/28  |  提交时间：2022/04/02
Alstonia scholaris  Indole alkaloids  Pulmonary fibrosis  Picrinine  Vallesamine  Scholaricine  19-Epischolaricine  FLIGHT MASS-SPECTROMETRY  ACUTE LUNG INJURY  AIRWAY INFLAMMATION  OXIDATIVE STRESS  BARK EXTRACTS  LEAVES  CONSTITUENTS  COLLAGEN  LEAF  KL-6  
C-19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 23, 页码: 16764-16769
作者:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Hu,Kun;  He,Ying-Jie;  Yang,Xing-Wei;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：79/37  |  提交时间：2022/04/02
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