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Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Huang, Jian-Ping;  Fang, Chengli;  Ma, Xiaoyan;  Wang, Li;  Yang, Jing;  Luo, Jianying;  Yan, Yijun;  Zhang, Yu;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1048Kb)  |  收藏  |  浏览/下载：190/46  |  提交时间：2019/10/28
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：193/66  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：215/66  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Horisfieldones A and B, Two Aromatic Ring-Contracted Dimeric Diarylpropanes with Human DOPA Decarboxylase Inhibitory Activity from Horsfieldia kingii 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 10, 页码: 3678-3681
作者:  Zhan, Rui;  Hu, You-Tian;  Shao, Li-Dong;  Qin, Xu-Jie;  Kuang, Fang;  Du, Shou-Zhen;  Wu, Fang;  Chen, Ye-Gao
浏览  |  Adobe PDF(2052Kb)  |  收藏  |  浏览/下载：128/23  |  提交时间：2019/07/29
Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 6
作者:  Dong, Fa-Wu;  Li, Fang;  Ren, Jia-Jia;  Zhao, Cheng-Mei;  Diao, Hong-Li;  Li, Bao-Jing;  Li, Yan-Ping;  Hu, Jiang-Miao;  He, Hong-Ping
浏览  |  Adobe PDF(798Kb)  |  收藏  |  浏览/下载：125/29  |  提交时间：2019/07/29
Valeriana amurensis  sesquiterpenoids  central nervous system  PC12 cells  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(4782Kb)  |  收藏  |  浏览/下载：148/57  |  提交时间：2019/07/29
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：251/17  |  提交时间：2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1