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雷公藤制剂肝毒性的机制及其调节作用研究 学位论文
, 2021
作者:  彭婉
Adobe PDF(6945Kb)  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/20
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
作者:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
浏览  |  Adobe PDF(1889Kb)  |  收藏  |  浏览/下载：100/52  |  提交时间：2022/04/02
cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
Secoiridoids and triterpenoids from the traditional Tibetan medicine Gentiana veitchiorum and their immunosuppressive activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 192, 页码: 112961
作者:  Guo,Kai;  Zhou,Ting-Ting;  Ren,Xue;  Li,Dan;  Hu,Hong;  Liu,Yan-Chun;  Liu,Yan;  Li,Sheng-Hong
Adobe PDF(1682Kb)  |  收藏  |  浏览/下载：79/28  |  提交时间：2022/04/02
Gentiana veitchiorum  Gentianaceae  Secoiridoids  Triterpenoids  Immunosuppressive activity  CONSTITUENTS  HEMSL.  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：65/13  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：99/49  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：62/23  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Multiple in vitro biological effects of phenolic compounds from Terminalia chebula var. tomentella 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 275, 页码: 114135
作者:  Zhang,Xiao-Rui;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Kong,Qing-Hua;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(2686Kb)  |  收藏  |  浏览/下载：88/16  |  提交时间：2022/04/02
Terminalia chebula var  tomentella  Combretaceae  Fructus Chebulae  Hydrolyzed tannins  Simple phenolic compounds  Anti-inflammation  Anti-diabetes  NITRIC-OXIDE  ANTIOXIDANT  TANNINS  CONSTITUENTS  VALIDATION  ALGORITHM  ESTERS  FRUITS  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载：65/28  |  提交时间：2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Discovery of potentially biased agonists of mu-opioid receptor (MOR) through molecular docking, pharmacophore modeling, and MD simulation 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2021, 卷号: 90, 页码: 107405
作者:  Jiang,Xuan;  Li,Shuxiang;  Zhang,Hongbin;  Wang,Liang-Liang
浏览  |  Adobe PDF(6441Kb)  |  收藏  |  浏览/下载：56/14  |  提交时间：2022/04/02
mu-Opioid receptors (MOR)  Biased ligands  Molecular docking  Hip-hop pharmacophore  MD simulation