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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
Authors:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
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Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
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Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
Authors:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
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Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 11
Authors:  Yakubu, Omolara F.;  Adebayo, Abiodun H.;  Dokunmu, Titilope M.;  Zhang, Ying-Jun;  Iweala, Emeka E. J.
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anticancer  Ricinodendron heudelotii  chemoprevention  
Renoprotective meroterpenoids from the fungus Ganoderma cochlear 期刊论文
FITOTERAPIA, 2019, 卷号: 132, 页码: 88-93
Authors:  Wang, Xin-Long;  Wu, Ze-Hong;  Di, Lei;  Zhou, Feng-Jiao;  Yan, Yong-Ming;  Cheng, Yong-Xian
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Ganoderma cochlear  Meroterpenoids  ECD calculations  Renal fibrosis  
Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation 期刊论文
CANCERS, 2018, 卷号: 10, 期号: 11, 页码: 18
Authors:  Ji, Xinyan;  Song, Lihua;  Sheng, Li;  Gao, Anhui;  Zhao, Yang;  Han, Shixun;  Zhang, Yuchao;  Zhu, Chu;  Zhao, Simeng;  Wang, Zhe;  Xu, Bohan;  Li, Li;  Li, Jia;  Tan, Ninghua;  Zhao, Bin
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hippo pathway  YAP  TAZ  RA-V  cancer  organ size  protein synthesis  
Seeing the light: Shifting from wild rhizomes to extraction of active ingredients from above-ground parts of Paris polyphylla var. yunnanensis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 期号: 1, 页码: 134-139
Authors:  Qin, Xu-Jie;  Ni, Wei;  Chen, Chang-Xiang;  Liu, Hai-Yang
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Paris Polyphylla Var. Yunnanensis  Rhizoma Paridis  Steroidal Saponins  Sustainable Utilization