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Natural product sciences: an integrative approach to the innovations of plant natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020
作者:  Shen, Yuemao;  Hao, Xiaojiang
浏览  |  Adobe PDF(4992Kb)  |  收藏  |  浏览/下载：88/14  |  提交时间：2021/01/05
12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 19, 页码: 2830-2836
作者:  Gui, Peng-Yan;  Yan, Xiao-Hui;  Yuan, Wen-Juan;  Ma, Yuan-Liang;  Ding, Xiao;  Liu, Shuai;  Di, Ying-Tong;  Zhu, Wei-Ming;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(919Kb)  |  收藏  |  浏览/下载：302/149  |  提交时间：2019/09/10
Harrisonia perforata  limonoid  12 beta-Acetyloxyperforatin  computational modelling  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1093Kb)  |  收藏  |  浏览/下载：182/44  |  提交时间：2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：284/35  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：247/33  |  提交时间：2019/04/15
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：350/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：400/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
作者:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
浏览  |  Adobe PDF(1966Kb)  |  收藏  |  浏览/下载：192/76  |  提交时间：2019/03/27
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：127/34  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
浏览  |  Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：519/146  |  提交时间：2016/12/21