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Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：108/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：405/0  |  提交时间：2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation  
Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1137, e1137
作者:  Liao, Y-J;  Bai, H-Y;  Li, Z-H;  Zou, J.;  Chen, J-W;  Zheng, F.;  Zhang, J-X;  Mai, S-J;  Zeng, M-S;  Sun, H-D;  Pu, J-X;  Xie, D.
Adobe PDF(5082Kb)  |  收藏  |  浏览/下载：560/55  |  提交时间：2014/05/16
Longikaurin a  Hepatocellular Carcinoma  Cell Cycle Arrest  Apoptosis  Skp2  
Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 7, 页码: e21930
作者:  Liu, Ying;  Chen, Xiao-Qin;  Liang, Heng-Xing;  Zhang, Feng-Xiang;  Zhang, Bo;  Jin, Jie;  Chen, Yong-Long;  Cheng, Yong-Xian;  Zhou, Guang-Biao
Adobe PDF(877Kb)  |  收藏  |  浏览/下载：426/114  |  提交时间：2012/03/16
Nf-kappa-b  Cell-cycle Control  Overcomes Drug-resistance  Centipeda-minima  Antitumor-activity  Kinase-activity  Human Cancer  In-vitro  Activation  Expression  
MOLECULAR.CELL.BIOLOGY 5TH.ED 专著
, 2003
H. Lodish
Adobe PDF(62274Kb)  |  收藏  |  浏览/下载：84/8  |  提交时间：2014/05/27