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Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3846-3852
Authors:  Hou, Bo;  Liu, Ze;  Yang, Xiao-Bei;  Zhu, Wen-Fei;  Li, Jin-Yu;  Yang, Liu;  Reng, Fu-Cai;  Lv, Yong-Feng;  Hu, Jiang-Miao;  Liao, Guo-Yang;  Zhou, Jun
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Dryocrassin ABBA  Neuraminidase  Total synthesis  Shanghai H7N9  Anhui H7N9  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
Authors:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 7, 页码: 1437-1446
Authors:  Zi, Cheng-Ting;  Yang, Dan;  Dong, Fa-Wu;  Li, Gen-Tao;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Jiang,ZH (reprint author),Yunnan Univ,Key Lab Med Chem Nat Resource,Kunming 650091,Peoples R China.;  zjiang@lakeheadu.ca;  hujiangmiao@mail.kib.ac.cn
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Podophyllotoxin  Epipodophyllotoxin  4 '-demethylepipodophyllotoxin  Butyrylated Glycosides  Antitumor  Cytotoxic  Synthesis  
Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11, 页码: 2966-2973
Authors:  Ni, Guanghui;  Li, Zhiyuan;  Liang, Kangjiang;  Wu, Ting;  De Libero, Gennaro;  Xia, Chengfeng
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Nkt Cells  Antigen  Lysophospholipids  Sar  
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
Authors:  Zhu, Jinmei;  Wu, Chun-Feng;  Li, Xiaobing;  Wu, Gui-Sheng;  Xie, Shan;  Hu, Qian-Nan;  Deng, Zixin;  Zhu, Michael X.;  Luo, Huai-Rong;  Hong, Xuechuan
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Alzheimer's Disease  Acetylcholinesterase  Butyrylcholinesterase  Molecular Modeling  2-aminobenzimidazole  
Synthesis, structure-activity relationships and biological evaluation of caudatin derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 9, 页码: 2877-2888
Authors:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Chen, Hao;  Guo, Rui-Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Synthesis  Caudatin Derivatives  Anti-hbv Activity  Structure-activity Relationships  
Introduction of aromatic group on 4 '-OH of alpha-GalCer manipulated NKT cell cytokine production 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 8, 页码: 2767-2776
Authors:  Zhang, Wenpeng;  Xia, Chengfeng;  Nadas, Janos;  Chen, Wenlan;  Gu, Li;  Wang, Peng George
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Alpha-galcer  Nkt Cell Ligand  Computer Modeling  Cd1d  Nkt Tcr  
Synthesis and biological assay of 4-aryl-6-chloro-quinoline derivatives as novel non-nucleoside anti-HBV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 4, 页码: 1400-1408
Authors:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Wang, Li-Jun;  Geng, Chang-An;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
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Hepatitis b Virus  4-aryl-6-chloro-quinoline  Derivatives  Synthesis  
Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 19, 页码: 6937-6941
Authors:  Yan, Jian;  Sun, Lirong;  Wu, Guisheng;  Yi, Ping;  Yang, Fumei;  Zhou, Lin;  Zhang, Xianmin;  Li, Zhongrong;  Yang, Xiaosheng;  Luo, Huairong;  Qiu, Minghua
Adobe PDF(368Kb)  |  Favorite  |  View/Download:346/127  |  Submit date:2012/03/21
Alzheimer's Disease  Hupzine a  Ache  Docking Study  
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 9, 页码: 4860-4871
Authors:  Zhao, Yu;  Guo, Na;  Lou, Li-Guang;  Cong, Yu-Wen;  Peng, Li-Yan;  Zhao, Qin-Shi
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Derivatives Of Taxchinin a And Brevifoliol  Synthesis  Cytotoxicity  Sar