中国科学院昆明植物研究所知识管理系统(KIB OpenIR): Search Results

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2010 [1]

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Funding Project：This dissertation is composed of four chapters, in which the chemical constituents of three medicinal plants, Abrus precatorius L., Echinops ritro L., and Saussurea laniceps Hand-Mazz. have been phytochemically studied. 150 compounds, including 10 new ones, were isolated from above mentioned three species. Their structures were established on the basis of extensive spectroscopic methods in conjunction with single-crystal X-ray diffraction analysis and computational methods. Chapter 4 is a review about the chemical constituentsand bioactivities from the plants genus Echinops of the family Compositae. These compounds include monoterpenes, sesquiterpenes (including guaiane and eudesmane mainly), triterpenoids, alkaloids, thiophenes, coumarins, steroids, lignans, flavones and its glycosides. A series of guaiane and eudesmane type sesquiterpenes have been isolated from Echinops ritro L., which is the first time in Echinops species. 21 substituted thiophenes (including 4 new ones) have been isolated from it. Some of them exhibited significant anti-microbial activity. As well as, one novel sulf-polyacetylene ester was isolated from Echinops ritro L.. The computational prediction of optical rotation values and 13C NMR chemical shift was attempted to elucidate structure of natural products. A series of sesquiterpenes have been isolated from Saussurea laniceps Hand-Mazz.

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