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An Approach for the Synthesis of Pyrazolo[1,5-a]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 18, 页码: 12762-12771
作者:  Ren,Jian;  Ding,Shihua;  Li,Xiaonian;  Bi,Ran;  Zhao,Qinshi
Adobe PDF(1469Kb)  |  收藏  |  浏览/下载：51/15  |  提交时间：2022/04/02
BIOLOGICAL EVALUATION  REGIOSELECTIVE SYNTHESIS  CASCADE REACTIONS  FUNCTIONALIZATION  DEHYDROGENATION  DISCOVERY  POTENT  BOND  SAR  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：356/39  |  提交时间：2017/12/18
Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：285/66  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：258/67  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Mechanisms of the dilator action of the Erigerontis Herba on rat aorta 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 155, 期号: 3, 页码: 1561-1567
作者:  Koon, Chi-Man;  Fong, Subiyanto;  Wat, Elaine;  Wang, Yan-Ping;  Cheung, David Wing-Shing;  Lau, Clara Bik-San;  Leung, Ping-Chung;  Sun, Han-Dong;  Zhao, Qin-Shi;  Fung, Kwok-Pui;  Fung,KP (reprint author),Chinese Univ Hong Kong,Sch Biomed Sci,Room 509A,Shatin,Hong Kong,Peoples R China.;  kpfung@cuhk.edu.hk
Adobe PDF(493Kb)  |  收藏  |  浏览/下载：189/55  |  提交时间：2014/11/25
Erigerontis Herba  Vasodilation  Aorta  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：654/97  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：285/59  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 9, 页码: 4860-4871
作者:  Zhao, Yu;  Guo, Na;  Lou, Li-Guang;  Cong, Yu-Wen;  Peng, Li-Yan;  Zhao, Qin-Shi
Adobe PDF(416Kb)  |  收藏  |  浏览/下载：290/114  |  提交时间：2011/11/24
Derivatives Of Taxchinin a And Brevifoliol  Synthesis  Cytotoxicity  Sar  
Synthesis and cytotoxicity of some new eriocalyxin B derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 卷号: 42, 期号: 4, 页码: 494-502
作者:  Zhao, Yu;  Niu, Xue-Mei;  Qian, Li-Ping;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Sun, Han-Dong
Adobe PDF(329Kb)  |  收藏  |  浏览/下载：306/114  |  提交时间：2011/11/24
Eriocalyxin b  Synthesis  Cytotoxicity  Sar  
New isoprenylated flavones, artochamins A-E, and cytotoxic principles from Artocarpus chama 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2004, 卷号: 67, 期号: 5, 页码: 757-761
作者:  Wang, YH;  Hou, AJ;  Chen, L;  Chen, DF;  Sun, HD;  Zhao, QS;  Bastow, KF;  Nakanish, Y;  Wang, XH;  Lee, KH
Adobe PDF(67Kb)  |  收藏  |  浏览/下载：1335/522  |  提交时间：2012/03/21
Paris-polyphylla Sm  Domestic Plants  Var Pluriflorum  Components  Glycosides  Rhizomes  Constituents  Spirostanol  Sapogenins  Leaves