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An Approach for the Synthesis of Pyrazolo[1,5-a]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 18, 页码: 12762-12771
作者:  Ren,Jian;  Ding,Shihua;  Li,Xiaonian;  Bi,Ran;  Zhao,Qinshi
浏览  |  Adobe PDF(1469Kb)  |  收藏  |  浏览/下载：57/15  |  提交时间：2022/04/02
BIOLOGICAL EVALUATION  REGIOSELECTIVE SYNTHESIS  CASCADE REACTIONS  FUNCTIONALIZATION  DEHYDROGENATION  DISCOVERY  POTENT  BOND  SAR  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：359/39  |  提交时间：2017/12/18
The Relationships between Chemical and Genetic Differentiation and Environmental Factors across the Distribution of Erigeron breviscapus (Asteraceae) 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11, 页码: e74490
作者:  Li, Xiang;  Peng, Li-yan;  Zhang, Shu-dong;  Zhao, Qin-shi;  Yi, Ting-shuang
Adobe PDF(516Kb)  |  收藏  |  浏览/下载：268/51  |  提交时间：2014/01/13
Temperature Stress  Aflp  Plant  Acid  Inhibition  Flavonoids  Diversity  Lactuceae  Extract  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：657/97  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11 beta-HSD1 inhibitors: Potential impact in diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 403-414
作者:  Deng, Xu;  Shen, Yu;  Yang, Jing;  He, Juan;  Zhao, Yu;  Peng, Li-Yan;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1215Kb)  |  收藏  |  浏览/下载：386/148  |  提交时间：2013/10/16
Ent-kaurene Diterpenoids  Structure-activity Relationship Studies  Selective 11 Beta-hsd1 Inhibitors  Urea Derivatives  Diabetes  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载：311/95  |  提交时间：2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis  
Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2007, 卷号: 121, 期号: 9, 页码: 2084-2094
作者:  Yu, Zu-Yin;  Liang, Yu-Guang;  Xiao, He;  Shan, Ya-Jun;  Dong, Bo;  Huang, Rui;  Fu, Ya-Li;  Zhao, Zhen-Hu;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Wang, Sheng-Qi;  Chen, Jia-Pei;  Mao, Bing-Zhi;  Cong, Yu-Wen
Adobe PDF(894Kb)  |  收藏  |  浏览/下载：279/75  |  提交时间：2011/11/24
Melissoidesin g  Leukemia  Apoptosis  Redox  Arsenic Trioxide