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The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：318/61  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：238/83  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 9, 页码: 1208-1217
作者:  Su, Xing-li;  Su, Wen;  Wang, Ying;  Wang, Yue-hu;  Ming, Xin;  Kong, Yi
浏览  |  Adobe PDF(2212Kb)  |  收藏  |  浏览/下载：143/61  |  提交时间：2017/01/05
Psm2  Selaginellaceae  Pyrrolidinoindoline Alkaloid  Antiplatelet  Antithrombosis  Pi3k/akt Signaling  
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 6, 页码: 752-758
作者:  Yan, Jian-hua;  Li, Qun-yi;  Boutin, Jean A.;  Renard, M. Pierre;  Ding, Yi-xiang;  Hao, Xiao-jiang;  Zhao, Wei-min;  Wang, Ming-wei
Adobe PDF(435Kb)  |  收藏  |  浏览/下载：339/99  |  提交时间：2011/12/19
Melanin-concentrating Hormone  Melanin-concentrating Hormone Receptor-1  Antagonist