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Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
作者:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin;  Bao,Wanrong;  Zheng,Hongming;  Wen,Xin;  Cheng,Huiyuan;  Fung,Hauyee;  Wong,Tinlong;  Zhao,Zhongzhen;  Lyu,Aiping;  Han,Quanbin;  Sun,Handong
收藏  |  浏览/下载:60/0  |  提交时间:2022/04/02
Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION  
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
Adobe PDF(10292Kb)  |  收藏  |  浏览/下载:228/28  |  提交时间:2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载:266/32  |  提交时间:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
ent-Kauranoids isolated from Isodon eriocalyx var. laxiflora and their structure activity relationship analyses 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 48, 页码: 9161-9171
作者:  Wang,Wei-Guang;  Yang,Jin;  Wu,Hai-Yan;  Kong,Ling-Mei;  Su,Jia;  Li,Xiao-Nian;  Du,Xue;  Zhan,Rui;  Zhou,Min;  Li,Yan;  Pu,Jian-Xin;  Sun,Han-Dong
浏览  |  Adobe PDF(1109Kb)  |  收藏  |  浏览/下载:210/50  |  提交时间:2016/01/19
Ent-kaurane  Diterpenoids  Isodon  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载:166/29  |  提交时间:2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 10
作者:  Jiang,Shiyou;  Du,Jiacheng;  Kong,Qinghua;  Li,Chaocui;  Li,Yan;  Sun,Handong;  Pu,Jianxin;  Mao,Bingyu
浏览  |  Adobe PDF(7288Kb)  |  收藏  |  浏览/下载:178/51  |  提交时间:2016/01/19
Xerophilusin B Induces Cell Cycle Arrest and Apoptosis in Esophageal Squamous Cell Carcinoma Cells and Does Not Cause Toxicity in Nude Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 1, 页码: 10-16
作者:  Yao, Ran;  Chen, Zhaoli;  Zhou, Chengcheng;  Luo, Mei;  Shi, Xuejiao;  Li, Jiagen;  Gao, Yibo;  Zhou, Fang;  Pu, Jianxin;  Sun, Handong;  He, Jie
浏览  |  Adobe PDF(6589Kb)  |  收藏  |  浏览/下载:245/57  |  提交时间:2015/06/29
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载:261/67  |  提交时间:2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Mechanisms of the dilator action of the Erigerontis Herba on rat aorta 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 155, 期号: 3, 页码: 1561-1567
作者:  Koon, Chi-Man;  Fong, Subiyanto;  Wat, Elaine;  Wang, Yan-Ping;  Cheung, David Wing-Shing;  Lau, Clara Bik-San;  Leung, Ping-Chung;  Sun, Han-Dong;  Zhao, Qin-Shi;  Fung, Kwok-Pui;  Fung,KP (reprint author),Chinese Univ Hong Kong,Sch Biomed Sci,Room 509A,Shatin,Hong Kong,Peoples R China.;  kpfung@cuhk.edu.hk
Adobe PDF(493Kb)  |  收藏  |  浏览/下载:191/55  |  提交时间:2014/11/25
Erigerontis Herba  Vasodilation  Aorta  
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
Adobe PDF(1121Kb)  |  收藏  |  浏览/下载:450/56  |  提交时间:2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin